The case of the vanishing splenial lesion

Hegde, Anaita Udwadia; Kei, Pin Lin; Ahuja, M S

doi:10.1259/bjr/42539289

Cited by 3 publications

(3 citation statements)

References 5 publications

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“…There are two types of lesion in the splenium: Boomerang [8,13] and oval shaped. [10,15] There were two cases each in the present study. The significance of the shape of lesions remains unclear.…”

Section: Discussionmentioning

confidence: 82%

Localized reversible high signal intensities on diffusion-weighted MRI in hypoglycemia: A study of 70 cases

et al. 2016

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Introduction:It is well-known that localized reversible high signal intensities in the splenium of the corpus callosum or the basal ganglia appear on diffusion-weighted MRI in the presence of hypoglycemia. The aim of this study was to clarify the incidence and significance of such high signal intensity lesions.Results:We analyzed 70 cases of hypoglycemia with consciousness disturbance referred to our outpatient office. Localized reversible high signal intensities on diffusion-weighted MRI were noted in 6 cases (8.6%). They were at the splenium of the corpus callosum in four cases (5.7%), and right frontal cortex and bilateral frontal white matter in one each. Convulsions were noted in five cases, and right hemiparesis was noted in three. None of the three cases of hemiparesis showed localized reversible high signal intensities on diffusion-weighted MRI. These lesions are reversible if the patients undergo treatment without delay.Conclusion:The significance of these lesions is still unclear. However, when a high signal intensity lesion that is not reasonable for the symptom is detected on diffusion-weighted MRI, an immediate check of the blood sugar level is mandatory.

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Section: Discussionmentioning

confidence: 82%

Localized reversible high signal intensities on diffusion-weighted MRI in hypoglycemia: A study of 70 cases

et al. 2016

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“…Transient splenial lesions (TSL) are seen in conditions with varied etiologies, including epilepsy, the usage as well as sudden withdrawal of antiepileptic drugs (AED), brain infarction, multiple sclerosis; cerebral trauma, neoplasm, adrenoleukodystrophy, AIDS dementia complex,[25–7] infections like influenza, measles, herpes, salmonella, mumps, adenovirus, varicella zoster, Legionnaires disease, rotavirus,[5] HIV, tubercular meningitis[3] and other conditions like hypoglycemia’[13] Marchiafava–Bignami syndrome, and hemolytic-uremic syndrome with encephalopathy. [8] Mild encephalitis/encephalopathy with a reversible isolated SCC lesion (MERS) is a recently described clinicoradiological syndrome with excellent prognosis.…”

Section: Discussionmentioning

confidence: 99%

“…[1–13] These reversible lesions are oval homogenous, non-hemorrhagic, and non-enhancing lesions seen in the central part of the splenium of the corpus callosum (SCC). The lesions are bright on T2W and FLAIR images; they are slightly hypointense on T1W images and show restricted diffusion.…”

Section: Introductionmentioning

confidence: 99%

Transient splenial lesion: Further experience with two cases

Singh

Gogoi

Vyas

et al. 2010

Indian Journal of Radiology and Imaging

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Transient splenial lesions (TSL) of the corpus callosum are uncommon radiologic findings that are seen in a number of clinical conditions with varied etiologies. They were first described a decade earlier in patients with epilepsy and hence were thought to be seizure or seizure therapy related. Subsequently, more cases were described by different observers in diseases with different etiologies, and the list is still increasing. Awareness of these lesions is necessary as they are an uncommon finding and have to be differentiated from other infective/noninfective causes. MRI is the imaging modality of choice as these lesions are not seen on routine noncontrast CT scan. The authors here describe two cases which showed TSL, with complete/partial resolution on follow-up scans. The authors also present a review of the literature.

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