The Beyond-Use Date Perception of Drugs in North Jakarta, Indonesia

Cokro, Fonny; Arrang, Sherly Tandi; Solang, Jonathan A. N.; Sekarsari, Pangestuning

doi:10.15416/ijcp.2021.10.3.172

Cited by 4 publications

(6 citation statements)

References 13 publications

(16 reference statements)

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“…Kusuma et al (2020) reported that the level of public knowledge related to the Beyond Use Date in Indonesia is still relatively low. This was also confirmed by Cokro et al (2021), who reported that the majority of the respondents examined (97%), did not know about BUD, and all respondents (100%) never received information on BUD from pharmacists. Some of the respondents have the perception that BUD is the same as the expiration date which is usually printed on the factory packaging.…”

Section: Introductionsupporting

confidence: 53%

“…Some of the respondents have the perception that BUD is the same as the expiration date which is usually printed on the factory packaging. Cokro et al (2021) concluded that the perception of the people of North Jakarta regarding BUD could be caused by the low knowledge of BUD, and thus, the role of pharmacists in informing and educating patients and the public about BUD is very necessary.…”

Section: Introductionmentioning

confidence: 99%

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Pharmacy student knowledge level regarding the beyond-use date

et al. 2023

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Background: In daily practice, misunderstandings often arise regarding the expiration date after opening the package of a drug. Beyond Use Date (BUD) is the time limit for using the drug after it has been formulated or prepared or after the primary packaging has been opened or damaged. Students need to understand BUD because BUD is related to the stability and quality of drug preparations. Without proper knowledge of BUD, the provision of information to patients may be misleading and it may lead to unsafe use of the drug. Objective: This study aims to determine the level of knowledge of pharmacy students about beyond use date of drugs. Methods: A descriptive survey is used in this observational cross-sectional study. The data collection was conducted in June 2022 at the Pharmacy Study Programme, Faculty of Health Sciences, the University of Muhammadiyah Mataram, Indonesia with a total sample of 163 students. Results: This study found that 42.9% (n:70) pharmacy students have a ‘good’ category of knowledge of BUD, while 53.9% (n: 88) have an ‘enough’ category of knowledge and 3.1% (n:5) have a ‘less' category of knowledge. A total of 11.1% (n:18) of students said BUD did not determine drug use, and 42.9% (n:70) said BUD and ED were not the same. Conclusion: The average level of knowledge of pharmacy students in the sampled university about Beyond Use Date Drugs is in the sufficient category.

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Section: Introductionsupporting

confidence: 53%

Section: Introductionmentioning

confidence: 99%

Pharmacy student knowledge level regarding the beyond-use date

et al. 2023

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“…However, a previous study on BUD knowledge of the North Jakarta community found that approximately 50% of the informants consider BUD and the expiration date similar. 6 This result shows that there is a need to promote Indonesian pharmacists on having sufficient BUD knowledge and delivering the information to patients. This study emphasizes the importance of repeating and updating BUD information through various education development programs regulated by The Indonesia Pharmacist Association.…”

Section: Discussionmentioning

confidence: 94%

“…According to the recent study by Cokro et al (2021), the comprehension of BUD among the North Jakarta community in Indonesia is extremely low, as only 3% have sufficient knowledge, and none of the respondent mentioned pharmacists as a source of BUD information. 6 This study aims to examine the prevalence of Indonesian pharmacists’ knowledge of BUD of various non-sterile compounding drugs since this problem has not been previously investigated.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of pharmacist knowledge on beyond-use date (BUD) of various non-sterile compounding drugs in Indonesia

et al. 2022

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Objective: In extemporaneous compounding, drugs’ stability is indicated by beyond-use date (BUD), which is different from the expiration date determined by manufacturers, hence, pharmacists are required to provide proper BUD information to patients. A recent study showed that BUD knowledge in the North Jakarta community is low, therefore, this study aims to examine the prevalence of Indonesian pharmacists’ BUD knowledge regarding various non-sterile dosage forms. Methods: This cross-sectional study involved Indonesian pharmacists’ knowledge of serving extemporaneous prescriptions. Recruitment was carried out through the purposive and snow-balling sampling method, while data were obtained by filling out a validated authors’ designed questionnaire, with total 34 questions, and collected in September 2021 and then analyzed using the chi-square test. Results: Among the 221 total respondents, 93.7% had BUD knowledge, while 12.7% responded that BUD and expiration date are similar. Regarding BUD for crushed tablets, dry syrup without preservatives, and ointment without moisture, there were 13.1%, 82.8%, and 29.4% responded rightly, respectively. Furthermore, there was no correlation between BUD knowledge and respondents’ characteristics, including health-care workplace and location, as well as gender, and age with p>0.05. Conclusion: Based on the results, the Indonesian pharmacists were considered to have inadequate BUD knowledge, specifically on crushed tablets and ointment, and this might affect drugs’ safety.

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“…A cross-sectional study conducted in Yogyakarta found that 75% of prescriptions intended for children can only be carried out through extemporaneous compounding due to the non-availability of readily made dosage forms, 8 hence, this re-emphasize that the knowledge of BUD is very important for patients. 9 According to Cokro et al 9 from a total of 60 informants, 97% know nothing about BUD, while 100% denied pharmacists’ role in providing related information. Therefore, there is a need to study BUD interventions from the pharmacist angle, that is, providing BUD information on drug labels and verbally.…”

Section: Introductionmentioning

confidence: 99%

Indonesian Pharmacists’ Application of Beyond-Use Date Interventions to Patients and Its Contributing Factors: A Cross-Sectional Study

et al. 2023

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Background: Extemporaneous preparations are commonly used in Indonesia, hence, Beyond-Use Date (BUD) information needs to be delivered by pharmacists to patients to maximize drug stability and enhance safety. Objective: This study aims to evaluate BUD interventions carried out by Indonesian pharmacists. Methods: A cross-sectional design was used, while a validated and reliable questionnaire was given to the samples using the snowballing and purposive sampling methods. The sample criteria were Indonesian pharmacists who had experience serving patients’ extemporaneous prescriptions and those that completed the questionnaire. The significance of the relationship between BUD interventions and samples’ characteristics was evaluated using the Mann-Whitney U test. Results: From the 221 total respondents, the majority admitted that they always provide BUD labeling on crushed tablets 46%, syrup 50.7%, and ointment 49.6% extemporaneous preparations. Similarly, most of the respondents also affirmed that they always provided BUD verbal information to patients on crushed tablets 66.8%, syrup 68%, and ointment 64% extemporaneous preparations. However, the remaining pharmacists, ranging from 32% to 54%, acknowledged that they did not always deliver both BUD labeling and verbal information to patients. Compared to the community-based, hospital pharmacists provided BUD labeling more frequently on all extemporaneous formulations as demonstrated by P < .05. Additionally, pharmacists found to work in Jakarta and the surrounding areas provided substantially more BUD labeling on crushed tablets and ointment ( P < .05) compared to other workplace. Adult pharmacists also provided BUD labeling on crushed tablet formulations more often than the middle-aged ( P < .05). Only the crushed tablet preparation was associated with the provision of BUD verbal information ( P = .004). Conclusions: Based on the results, not all pharmacists verbally inform patients about BUDs nor provide drug labeling on various extemporaneous preparations. The determinant factors contributing to BUD labeling provisions were the type of practice, workplace location, and age. For the provision of verbal information, the only determinant factor was the type of practice.

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The Beyond-Use Date Perception of Drugs in North Jakarta, Indonesia

Cited by 4 publications

References 13 publications

Pharmacy student knowledge level regarding the beyond-use date

Pharmacy student knowledge level regarding the beyond-use date

Prevalence of pharmacist knowledge on beyond-use date (BUD) of various non-sterile compounding drugs in Indonesia

Indonesian Pharmacists’ Application of Beyond-Use Date Interventions to Patients and Its Contributing Factors: A Cross-Sectional Study

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