The background of cancer of the corpus

Corscaden, James A.; Gusberg, S.B.

doi:10.1016/0002-9378(47)90404-3

Cited by 70 publications

(10 citation statements)

References 21 publications

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“…The rates in the Western countries are rising [2], Risk factors for this disease are the following: over weight [13,14], nulliparity [15], diabetes [15] and hyper tension [16,17].…”

Section: Discussionmentioning

confidence: 99%

Treatment of Precursors of Endometrial Cancer

Mecke

Lüttges²,

Lehmann-Willenbroock

et al. 1994

Gynecol Obstet Invest

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From 1985 to 1991, 73 hysterectomies were performed on patients suffering from histologically demonstrated adenomatous hyperplasia, grades 1–3, at the Kiel University Hospital of Gynecology. The operations were done within a month from the diagnosis. Three of the patients were under 40 years of age. An exact correspondence between the grade of adenomatous hyperplasia in the abraded material and the uterus specimen was found in only 44% of the cases. In the patients over 40 with adenomatous hyperplasia of any grade demonstrated in the abraded material, an already well-differentiated endometrial carcinoma was found in 16% of the cases, while such a carcinoma was found in 57% of the cases with grade 3 adenomatous hyperplasia! Even though drug therapy with gestagen may have a beneficial effect, a hysterectomy is nevertheless the treatment of choice for adenomatous hyperplasia of grade 2 and grade 3 in patients over 40 because it is not absolutely certain from a diagnostic point of view that the material is representative of the entire mucosa. In women under 40 years of age it is necessary to plan therapy on an individual basis.

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“…The rates in the Western countries are rising [2], Risk factors for this disease are the following: over weight [13,14], nulliparity [15], diabetes [15] and hyper tension [16,17].…”

Section: Discussionmentioning

confidence: 99%

Treatment of Precursors of Endometrial Cancer

Mecke

Lüttges²,

Lehmann-Willenbroock

et al. 1994

Gynecol Obstet Invest

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show abstract

“…This has been studied by Corscaden and Gusberg (1947), Palmer et al (1949), Randall and Gerhardt (1954) and Way (1954) in relation to carcinoma of the body of the uterus from two aspects, namely the average age when menstruation ceased and the percentage of cases who menstruated after the age of 50. 6c Way (1954) and others give figures for the normal menopause, the average age being 46 * 5 while 31 per cent menstruate after the age of 50.…”

Section: The Menopausementioning

confidence: 99%

“…IN the last two decades, Corscaden and Gusberg (1947), Palmer et al (1949) and Way (1954), reviewing cases of carcinoma of the body of the uterus, have shown that there is an increased tendency to other lesions in these patients, some of them gynaecological and some not. Thus carcinoma of the body of the uterus would seem to occur more frequently in a certain type of person.…”

Section: Introductionmentioning

confidence: 99%

A Gynaecological Study of 800 Diabetics

Noble

Attwood

1958

BJOG

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“…Urinary-bladder epithelium showed cystitis cystica in eight of sixteen cancer rases adequately studied (50 per cent). Gastric polyps were present in two women of the cancer group, benign polyps of No. 3 ENDOCRINES & ENDOMETRIAL CA.…”

Section: S O~n M E R S C H Meissnes 517mentioning

confidence: 99%