The association of the Syntax score II with carotid intima media thickness and epicardial fat tissue

Aksu, Uğur; Gülcü, Oktay; Bilgi, Zeynep; Topçu, Selim; Sevimli, Serdar; Bayram, Ednan; Tanboğa, İbrahi̇m Hali̇l

doi:10.1016/j.ihj.2017.04.008

Cited by 7 publications

(6 citation statements)

References 32 publications

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“…Avci et al found a positive correlation between Syntax score I, three-vessel disease, and carotid stenosis [26]. A similar correlation between the intima-media thickness of the carotid artery and Syntax score I and II was reported by the teams of Saedi et al, Ikeda et al, Aksu et al, and Korkmaz et al [27], [28], [29], [30]. The results of Ozturk and Sahin and Costanzo et al and col [31], [32], [33] are opposing.…”

Section: Discussionsupporting

confidence: 53%

Survival and Prognostic Factors After Carotid Artery Stenting in Patients with Concomitant Coronary Disease

Goranov

Tokmakova

Nikolov

2021

Open Access Maced J Med Sci

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AIM: The aim of the study was to analyze the prognostic factors in patients after carotid artery stenting (CAS). METHODS: In 329 patients after CAS, the median survival (MS) and overall survival (OS) were calculated for a follow-up period of 2–101 months. All patients underwent coronary angiography before carotid stenting and, if indicated, coronary revascularization. Four groups of factors were analyzed: Carotid disease, coronary artery disease (CAD), underlying cardiac pathology, and concomitant diseases. RESULTS: MS in all patients was 86 months, OS at 1, 3, 5, and 9 years was - 94%, 85%, 73%, and 51%, respectively. Event free survival was 85 months. Log Rank-Mantel-Cox analysis demonstrated significantly reduced MS in 21 tested factors, most of them related to CAD. Two-step multifactorial Cox regression analysis defined only 7 of them as independent prognostic factors for the survival of patients after CAS: Left main stenosis, complete revascularization, late myocardial infarction, stroke, age over 70 years, valvular disease, and carotid score. CONCLUSION: Survival of patients after CAS is limited mainly by CAD and underlying cardiac pathology. Staged revascularization treatment strategy may improve the prognosis and survival of patients with both carotid and coronary disease.

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Section: Discussionsupporting

confidence: 53%

Survival and Prognostic Factors After Carotid Artery Stenting in Patients with Concomitant Coronary Disease

Goranov

Tokmakova

Nikolov

2021

Open Access Maced J Med Sci

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“…Several studies demonstrated a close association between CIMT and SS I [9-11] . A recent study showed that CIMT correlated with SS II [12] . Two previous studies concluded that SS I is not a predictor of CAS [13,14] .…”

Section: Discussionmentioning

confidence: 99%

Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis

Öztürk¹,

Şahın²

2019

Braz J Cardiovasc Surg

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ObjectiveTo evaluate the predictive accuracy of SYNTAX score (SS) I and II for detecting significant carotid artery stenosis (CAS) in patients with multivessel coronary artery disease undergoing coronary artery bypass grafting (CABG) surgery.MethodsThe study population consisted of 416 patients. Clinical, demographic, and radiological records were retrospectively reviewed. Characteristics of patients with CAS (n=66) and patients without CAS (n=350) were compared before and after propensity score matching analysis.ResultsPatients with significant CAS were older compared to those without significant CAS [(60 (53-65) vs. 63 (59-67); P=0.01]. However, atherosclerotic risk factors and SS I were similar between groups. SS II CABG and percutaneous coronary intervention (PCI) were significantly higher in patients with CAS [37.4 (30.9-43.5) vs. 33.8 (29.9-38.9); P=0.02]. After propensity score matching analysis (66 vs. 66), age, SS II PCI and CABG were significantly higher in patients with CAS than those without CAS [37.4 (30.9-43.5) vs. 33 (29.3-36.9); P=0.03]. Age, SS II PCI and CABG were associated with CAS in logistic regression analysis [OR=1.086, 95% CI (1.032-1.143), P<0.001; OR=1.054, 95% CI (1.010-1.101), P=0.02; OR=1.078, 95% CI (1.029-1.129), P<0.01].In ROC curve analysis, SS II PCI >33.1 had 68.2% sensitivity and 54.6% specificity [AUC=0.624, P=0.01, 95% CI (0.536-0.707)] whereas SS II CABG >26.1 had 81.8% sensitivity and 54.6% specificity [AUC=0.670, P<0.01, 95% CI (0.583-0.749)] to predict CAS. Pairwise comparison of ROC curves revealed similar statistical accuracy for prediction of CAS (z statistic: 0.683, P=0.49)ConclusionSS II is useful to predict asymptomatic CAS in patients with multivessel coronary artery disease.

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“…The relationship between SS II and CrAD provides an advantage for having an opinion about CrAD without imaging. Aksu et al 26 investigated the relationship between SS II and carotid intima–media thickness (cIMT) and epicardial fat tissue (EFT). The authors compared low and high SS II groups after they had specified a median SS II value.…”

Section: Discussionmentioning

confidence: 99%

The Association Between SYNTAX Score II and Carotid Artery Disease Severity in Patients Who Underwent Coronary Artery Bypass Grafting

et al. 2019

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The SYNTAX score (SS) and SS II, which include additional clinical parameters, are widely used today for deciding revascularization following coronary angiography. We investigated the association between the presence and severity of carotid artery disease (CrAD) using the SS and SS II in 287 patients who underwent coronary artery bypass grafting. We based this investigation on the known association between coronary artery disease and CrAD. A significant association was observed between the groups with and without CrAD in terms of SS II values (28.4 ± 9.6 vs 21.4 ± 7.7, respectively; P < .001). A significant difference was also observed when stenosis was classified according to severity as <50%, 50% to 70%, and >70% ( P < .001). The results indicated a positive correlation between the presence and severity of CrAD as SS II increased ( r = 0.187, P = .005). According to the results of multivariate logistic regression analysis, the SS II was an independent predictor of CrAD.

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The association of the Syntax score II with carotid intima media thickness and epicardial fat tissue

Cited by 7 publications

References 32 publications

Survival and Prognostic Factors After Carotid Artery Stenting in Patients with Concomitant Coronary Disease

Survival and Prognostic Factors After Carotid Artery Stenting in Patients with Concomitant Coronary Disease

Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis

The Association Between SYNTAX Score II and Carotid Artery Disease Severity in Patients Who Underwent Coronary Artery Bypass Grafting

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