The Antibody Response of Guinea Pigs to Epidemic Typhus Vaccines of Various Antigenicities

Abstract

In previous studies it was indicated that vaccines showing especially high protective powers in the "guinea pig test" also induce in these animals high titers of the complement-fixing antibodies (Donovick and Wyckoff, 1942a, TABLE 1 The antibody response of guinea pigs vaccinated with epidemic typhus vaccines having antigenic titers of 1:8 LOT NO. 0? VACCINE 27 31 32 34 35 39 40 41 43* * These lots show 3+ complement fixation at 1:16 dilution as antigens.