THE ANTIBACTERIAL EFFECT OF ROSELLE (Hibiscus sabdariffa) EXTRACT AGAINST Staphylococcus epidermidis IN VITRO

Lusida, Terrence Timothy Evan; Hermanto, Bambang; Sudarno, Sudarno

doi:10.20473/ijtid.v6i4.3757

Cited by 3 publications

(4 citation statements)

References 10 publications

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“…The increasing of roselle calyces extract dose will cause decreasing of viscosity and indicating an increase of mucolytic activity, therefore, the mucolytic activity of roselle calyces extract was dose dependent. This is in accordance with previous studies of roselle calyces, which provide a various increasing activity with the increase of concentrations or doses, such as immunomodulation (Kadri et al, 2013), hepatoprotective (Ezzat et al, 2016), cardioprotective (Obouayeba et al, 2015), antidiabetic (Rosemary et al, 2014), antibacterial (Lusida et al, 2017), anticancer (Prabhakaran et al, 2017), antihypertensive (Abubakar et al, 2015), antinociceptive (Ali et al, 2011), antiinflammatory (Ali et al, 2011;Obouayeba et al, 2015), and antidiarrheal (Ali et al, 2011).…”

Section: Resultssupporting

confidence: 90%

“…Roselle calyces has many pharmacological effects that have been studied in silico, in vitro, in situ and/or in vivo, including: immunomodulation (Kadri et al, 2013), hepatoprotective (Ezzat et al, 2016), cardioprotective (Obouayeba et al, 2015), antidiabetic (Rosemary et al, 2014), antibacterial (Lusida et al, 2017), anticancer (Prabhakaran et al, 2017), antihypertensive (Abubakar et al, 2015), antimalarial (Nerdy, 2017), antinociceptive (Ali et al, 2011), anti-inflammatory (Ali et al, 2011;Obouayeba et al, 2015), and antidiarrheal (Ali et al, 2011). However, the mucolytic activity of roselle calyces has not been reported yet.…”

Section: Introductionmentioning

confidence: 99%

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MUCOLYTIC ACTIVITY OF ROSELLE (Hibiscus sabdariffa L.) CALYCES EXTRACT ON COW INTESTINAL MUCUS

Nerdy¹,

Manurung

2018

J Kedokt Hewan

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This study aimed to examine the mucolytic activity of roselle calyces extract on cow intestinal mucus in vitro. The extraction of rosellecalyces was performed by the subsequence maceration method using different polarity solvent (n-hexane, ethyl acetate, and methanol). Mucolyticactivity of each extract was evaluated by measuring the viscosity of mixture of cow intestinal mucus and phosphate buffer pH 7 compared toacetylcysteine as the standard mucolytic drug. The result showed that the decreasing of cow intestinal mucus and phosphate buffer pH 7 mixturesviscosity was indicated the increasing of mucolytic activity. The n-hexane, ethyl acetate, and methanol extract of roselle calyces exhibit dosedependentmucolytic activity. Mucolytic activity of roselle calyces ethyl acetate extract with dose of 0.8% and roselle calyces methanol extractwith dose of 0.6% showed no significant difference to mucolytic activity from acetylcysteine with dose of 0.1% (positive control). An increaseddose of roselle calyces extract will decrease the viscosity of cow intestinal mucus and phosphate buffer pH 7 mixtures, indicating an increase inmucolytic activity.

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Section: Resultssupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

MUCOLYTIC ACTIVITY OF ROSELLE (Hibiscus sabdariffa L.) CALYCES EXTRACT ON COW INTESTINAL MUCUS

Nerdy¹,

Manurung

2018

J Kedokt Hewan

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“…Penentuan KHM dilakukan dengan pengamatan kekeruhan secara visual. Nilai KHM ditentukan pada konsentrasi terkecil larutan yang jernih sehingga menandakan adanya penghambatan terhadap pertumbuhan bakteri [10].…”

Section: Penentuan Konsentrasi Hambat Minimumunclassified

“…Media diinkubasi selama 24 jam, kemudian dihitung jumlah koloninya. Nilai KBM ditentukan pada konsentrasi terkecil yang mampu membunuh 99,9% bakteri [10].…”

Section: Penentuan Konsentrasi Bunuh Minimumunclassified

Uji Aktivitas Antibakteri Ekstrak Etil Asetat Terong Ungu (Solanum melongena L.) terhadap Bakteri Staphylococcus epidermidis ATCC 12228

et al. 2023

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Staphylococcus epidermidis is the bacterium that most often causes infections in hospitals (Health care Associated Infections) and frequently found to be resistant to antibiotics, making them hard to treat. Purple eggplant (Solanum melongena L.) is one of the natural ingredients widely used as a food ingredient in the community with its antibacterial effect is known. This study aimed to determine the activity of purple eggplant ethyl acetate extract as an antibacterial for Staphylococcus epidermidis ATCC 12228. This research is an experimental study using the microdilution method to determine the minimum inhibitory concentration (MIC) and the spread plate method to determine the minimum bactericidal concentration (MBC) of the purple eggplant ethyl acetate extract against S. epidermidis ATCC 12228. The extract concentrations used were 5 mg/mL, 10 mg/mL, 20 mg/mL, 40 mg/mL, negative control, 10% DMSO control, and media control. The results showed that the MIC and MBC value of purple eggplant ethyl acetate extract against S. epidermidis ATCC 12228 were 10 mg/mL and 20 mg/mL, respectively. Increasing percentage of inhibition in line with the concentration used. Purple eggplant ethyl acetate extract has the potential as an antibacterial for S. Epidermidis ATCC 12228.

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Food use of whole and extracts of Hibiscus sabdariffa

Mahunu

Tahir

Osei-Kwarteng

et al. 2021

Roselle (Hibiscus Sabdariffa)

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THE ANTIBACTERIAL EFFECT OF ROSELLE (Hibiscus sabdariffa) EXTRACT AGAINST Staphylococcus epidermidis IN VITRO

Cited by 3 publications

References 10 publications

MUCOLYTIC ACTIVITY OF ROSELLE (Hibiscus sabdariffa L.) CALYCES EXTRACT ON COW INTESTINAL MUCUS

MUCOLYTIC ACTIVITY OF ROSELLE (Hibiscus sabdariffa L.) CALYCES EXTRACT ON COW INTESTINAL MUCUS

Uji Aktivitas Antibakteri Ekstrak Etil Asetat Terong Ungu (Solanum melongena L.) terhadap Bakteri Staphylococcus epidermidis ATCC 12228

Food use of whole and extracts of Hibiscus sabdariffa

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