The anesthetic effects of MS-222 (tricaine methanesulfonate) on some hematological parameters of sterlet, Acipenser ruthenus

Bishkoul, Gholam Reza; Halimi, Mostafa; Norousta, Rouhallah; Zamani, Navid; Heidari, Leila

doi:10.1007/s00580-013-1862-x

Cited by 6 publications

(3 citation statements)

References 20 publications

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“…Ko et al [ 27 ] reported a concentration-related decrease in Ht, Hb, and RBC of Platichthys stellatus intoxicated with hexavalent chromium and attributed these changes to hemophilia, osmoregulatory disturbances, or a direct adverse effect of Cr on hematopoietic stem cells. According to Bishkoul et al [ 28 ], anesthesia with MS-222 caused a decrease in Hb, Ht, and RBC in Acipenser ruthenus . According to Dawood et al [ 29 ], deltamethrin caused a decrease in Hb and RBC in Oreochromis niloticus .…”

Section: Hematological Analysis In Fish Toxicologymentioning

confidence: 99%

Hematological and Hematopoietic Analysis in Fish Toxicology—A Review

Witeska

Kondera

Bojarski

2023

Animals

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Hematological analysis is commonly used to assess the physiological state of fish. It includes red blood cell parameters, white blood cell parameters, and the number of thrombocytes per blood volume unit. Hematological analysis is one of the basic tools (often accompanied by biochemical and histopathological analyses) to assess the influence of organic and inorganic substances on fish. It is, therefore, applicable in both ecotoxicology and pharmacotoxicology. The advantages of this research method are the lack of need for specialized laboratory equipment and low costs, and the limitations are the need for extensive experience among the personnel performing the tests. One of the recommended methods of supplementing routinely determined hematological parameters is assessing the cellular composition and activity of hematopoietic tissue. As there is very little scientific data available on the issue of the effects of xenobiotics on the cellular structure of fish head kidney hematopoietic tissue, filling this gap should be considered an urgent need. Therefore, we recommend conducting research with the simultaneous use of hematological and hematopoietic analysis as reliable and complementary methods of assessing the impact of toxic substances on fish.

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Section: Hematological Analysis In Fish Toxicologymentioning

confidence: 99%

Hematological and Hematopoietic Analysis in Fish Toxicology—A Review

Witeska

Kondera

Bojarski

2023

Animals

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“…Limsuwan et al (12) observed increases in hematocrit, hemoglobin concentration, and erythrocyte count in Ictalurus punctatus and Witeska et al (18) found an increase in mean cell hemoglobin level and frequency of abnormal erythrocytes in Cyprinus carpio treated with etomidate, while Kazun and Siwicki (5) reported no change in the values of hematological parameters in eight other species of fish. According to Gressler et al (14), MS-222 induced hematocrit increase in Rhamdia quelen, while Bishkoul et al (19) observed reduction in hemoglobin concentration and hematocrit accompanied by erythropenia and leukopenia in Acipenser ruthenus subjected to this anesthetic. Limited data are available on the effects of etomidate and tricaine on immune responses in fish.…”

mentioning

confidence: 98%

Hematological effects of etomidate and tricaine in common carp

Witeska¹,

Teodorczuk²,

Ługowska³

2017

Turk J Vet Anim Sci

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“…Bishkoul et al. () reported a significant decrease in Hct, Hb, and RBC count in Sterlet Acipenser ruthenus immediately after exposure to MS‐222 (5 mg/L). However, Johnson et al.…”

mentioning

confidence: 99%

Sedative Efficacy of Tobacco Extract, Clove Oil, Tricaine Methanesulfonate, and Ketamine: Effects on Hematological Parameters and Blood Biochemical Profile in Sterlet

et al. 2019

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This study was carried out to evaluate the efficacy of four sedatives, including tobacco extract, clove oil, tricaine methanesulfonate (MS‐222), and ketamine, in juvenile Sterlet Acipenser ruthenus by use of two experiments. First, fish with an average weight (±SD) of 64.1 ± 3.4 g were exposed to immersion at six concentrations of each sedative, including clove oil at 14, 35, 56, 77, 98, and 119 mg/L; MS‐222 at 45, 50, 55, 60, 65, and 70 mg/L; ketamine at 35, 37.5, 40, 42.5, 45, and 50 mg/L; and tobacco extract at 375, 450, 525, 600, 675, and 700 mg/L. Induction time (deep induction) and recovery time were measured, and the concentrations inducing lower induction time and recovery (i.e., optimum concentrations) of each sedative were obtained as follows: 56 mg/L for clove oil, 60 mg/L for MS‐222, 45 mg/L for ketamine, and 675 mg/L for tobacco extract. To evaluate the impact of the selected concentration of each sedative on physiological responses of Sterlet, the hematological indices, plasma cortisol, glucose, and lactate concentrations were measured. Additionally, one nonexposed group was considered as a control group. Significant changes were revealed in all hematological parameters except for mean corpuscular hemoglobin concentration and monocytes percent. Biochemical parameters were measured at 0, 1, 3, and 6 h after induction. Significant changes were found in cortisol and lactate levels for all treatments except clove oil. Glucose concentration changed significantly only in the control group. Given that fish sedated with clove oil did not indicate changes in blood chemistry, clove oil may be the more effective sedative according to our results.

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The anesthetic effects of MS-222 (tricaine methanesulfonate) on some hematological parameters of sterlet, Acipenser ruthenus

Cited by 6 publications

References 20 publications

Hematological and Hematopoietic Analysis in Fish Toxicology—A Review

Hematological and Hematopoietic Analysis in Fish Toxicology—A Review

Hematological effects of etomidate and tricaine in common carp

Sedative Efficacy of Tobacco Extract, Clove Oil, Tricaine Methanesulfonate, and Ketamine: Effects on Hematological Parameters and Blood Biochemical Profile in Sterlet

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