The addition of synthesized hydroxyapatite and fluorapatite nanoparticles to a glass-ionomer cement for dental restoration and its effects on mechanical properties

Barandehfard, Faranak; Rad, M. Kianpour; Hosseinnia, A.; Khoshroo, Kimia; Tahriri, Mohammadreza; Jazayeri, Hossein E.; Moharamzadeh, Keyvan; Tayebi, Lobat

doi:10.1016/j.ceramint.2016.08.122

Cited by 67 publications

(60 citation statements)

References 54 publications

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“…Many researches have shown that the mechanical behavior of GIC would be definitely changed by additives, such as CHX and nanoparticles [ 19 , 31 , 32 , 33 , 34 ]. As a restorative material available in various conditions and usually applied as fissure sealing for posterior tooth [ 8 ], modified-GIC ought to have adequate mechanical and physical properties to resist occlusal forces while enhancing antibacterial ability.…”

Section: Resultsmentioning

confidence: 99%

Effects of Chlorhexidine-Encapsulated Mesoporous Silica Nanoparticles on the Anti-Biofilm and Mechanical Properties of Glass Ionomer Cement

Yan

Yang

et al. 2017

Molecules

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One of the primary causes for the failure of glass ionomer cement (GIC) is secondary caries. To enhance the anti-microbial performance of GIC without affecting its mechanical properties, chlorhexidine (CHX) was encapsulated in expanded-pore mesoporous silica nanoparticles (pMSN) to synthesize CHX@pMSN. CHX@pMSN was added at three mass fractions (1%, 5%, and 10% (w/w)) to GIC powder as the experimental groups. Pure GIC was set as the control group. The mechanical and anti-biofilm properties of GIC from each group were tested. The results demonstrated that CHX was successfully encapsulated on/into pMSN, and the encapsulating efficiency of CHX was 44.62% in CHX@pMSN. The anti-biofilm ability was significantly enhanced in all experimental groups (p < 0.001) compared with that in the control group. CHX was continuously released, and anti-biofilm ability was maintained up to 30 days. In addition, the mechanical properties (compressive strength, surface hardness, elastic modulus, water sorption, and solubility) of 1% (w/w) group were maintained compared with those in the control group (p > 0.05). In conclusion, adding 1% (w/w) CHX@pMSN to GIC led to conspicuous anti-biofilm ability and had no adverse effect on the mechanical properties of this restorative material. This study proposes a new strategy for preventing secondary caries by using CHX@pMSN-modified GIC.

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Section: Resultsmentioning

confidence: 99%

Effects of Chlorhexidine-Encapsulated Mesoporous Silica Nanoparticles on the Anti-Biofilm and Mechanical Properties of Glass Ionomer Cement

Yan

Yang

et al. 2017

Molecules

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“…One strategy proven to enhance mechanical performance is to modify the glass powder by adding materials such as metal powder 9,10) , bioactive glass 11) , and nano-bioceramics 12) . Another strategy that has demonstrated dramatically enhanced mechanical performance involves modifing polyacid by introducing activated chemical materials, such as amino acid derivatives 13,14) , N-vinylpyrrolidone 15) , and acrylate with other branched chains 16) , to the polyacid backbone.…”

Section: Introductionmentioning

confidence: 99%

Synergistic effects of titanium dioxide and cellulose on the properties of glassionomer cement

Sun

Zhu

et al. 2019

Dent. Mater. J.

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In this study, we evaluate the effect of co-doping with TiO2 nanoparticles and sisal cellulose nanocrystals (CNCs) on the physical and biological properties of a conventional glass-ionomer cement (GIC). Test samples were characterized by scanning electron microscopy, and Fourier-transform infrared spectroscopy, and subjected to mechanical tests to evaluate the mechanical performances. Antimicrobial activity was evaluated against Candida albicans, and cytotoxicity experiments were conducted using L-929 cells. Unmodified GIC served as a control. Compared with the control group, the co-doped group demonstrated an increased compressive strength of 18.9%, an increased shear bond strength of 51%, the dissolution decreased by 18.3%, the volume wear rate was reduced by 5%. The antifungal effect against C. albicans was increased by 22%. In cytotoxicity experiments, the co-doped group had a slightly negative effect on the viability of L-929 cells.

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“…It was found that the addition of fluoride ions into hydroxyapatite structure increases its resistance to biodegradability significantly (Joughehdoust et al 2010 ). In addition, by better absorption of protein, it expresses a stronger cellular connection and reinforces the activity of phosphates to create stronger osteoconductivity (Barandehfard 2016 ; Santos 2016 ). When OH − groups in HA are completely exchanged with F − groups, fluorapatite [Ca 10 (PO 4 ) 6 F 2 ] is formed (Shen 2016 ), which has more chemical and structural constancy compared with hydroxyapatite (Joughehdoust et al 2010 ; Sumathi 2015 ; Shen 2016 ).…”

Section: Introductionmentioning

confidence: 99%

Synthesis and evaluation of the bioactivity of fluorapatite–45S5 bioactive glass nanocomposite

2019

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This research study concerns the evaluations of nano-biocomposite ceramics’ characteristics and biocompatibility. A nanocomposite with 45S5 bioactive glass base has been synthesized by sol–gel method. The synthesized nanocomposites were characterized with the help of different techniques, using field-emission scanning electron microscope, X-ray powder diffraction, energy-dispersive X-ray spectroscopy to evaluate the crystal structure, microstructure, and the morphology of the nanocomposite. The results indicated that the synthesis of 45S5 bioactive glass–fluorapatite nanocomposites produced an average particle size of about 20–30 nm and percentages of crystallinity of about 70–90%. fluorapatite–45S5 bioactive glass nanocomposites were characterized in terms of their degradation by determining the weight change percentages, pH changes, the ion release and in terms of bioactivity by checking the apatite layer formation using a solution of simulated body fluid (SBF). The results showed non-cytotoxicity and the formation of a thick apatite layer on the synthesized nanocomposites within 28 days after soaking in SBF. This is an indication of desirable bioactivity in the synthesized particles.

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The addition of synthesized hydroxyapatite and fluorapatite nanoparticles to a glass-ionomer cement for dental restoration and its effects on mechanical properties

Cited by 67 publications

References 54 publications

Effects of Chlorhexidine-Encapsulated Mesoporous Silica Nanoparticles on the Anti-Biofilm and Mechanical Properties of Glass Ionomer Cement

Effects of Chlorhexidine-Encapsulated Mesoporous Silica Nanoparticles on the Anti-Biofilm and Mechanical Properties of Glass Ionomer Cement

Synergistic effects of titanium dioxide and cellulose on the properties of glassionomer cement

Synthesis and evaluation of the bioactivity of fluorapatite–45S5 bioactive glass nanocomposite

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