The Acne Problem

Becker, Frederic T.

doi:10.1001/archderm.1953.01540020051010

Cited by 20 publications

(2 citation statements)

References 15 publications

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“…Whereas some authors reported only staphylococci similar to those found on the skin from seborrheic areas of normal subjects [234], others found Corynebacterium and staphylococci, while others described the acne microflora made of 4 genera of microorganisms: P. acnes , Staphylococcus , Micrococcus , and Pityrosporon [235]. Few authors even considered acne lesions sterile [236].…”

Section: From Acne Microbacillus To P Acnes: Facts Controversies Anmentioning

confidence: 99%

Acne Pathogenesis: History of Concepts

Tilles¹

2014

Dermatology

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From the first reliable descriptions of acne in the early 19th century, dermatologists recognized it as a disease of the pilosebaceous follicle. Until the middle of the 20th century, they hypothesized that seborrhoea, follicular keratosis and microorganisms could be individually responsible for the acne lesions. Inflammation was only regarded as the final and inescapable step of the acne process. Although the importance of these factors has been reevaluated, recent works still regarded them as mandatory. In the 1970s, the onset of isotretinoin dramatically improved acne management. It also provided great opportunities for a better understanding of the pathogenic factors of acne. This study analyzes their genesis and development from the seminal contributions until recent advances.

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Section: From Acne Microbacillus To P Acnes: Facts Controversies Anmentioning

confidence: 99%

Acne Pathogenesis: History of Concepts

Tilles¹

2014

Dermatology

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“…In view of these findings In reviewing the literature, numerous controversial reports on the levels of total urinary I7-KS in patients with acne were found [1,4,26,33,44,45]. Most of these studies utilized older, less accurate techniques and assayed only total urinary 17-KS, not fractional 17-KS.…”

Section: -Desoxymentioning

confidence: 99%