“…These observations have predominantly been described in case reports. The agents include cytotoxic chemotherapies and antimetabolites (chlorambucil and cyclophosphamide) [30,39,148,200,251,360,390], immunoglobulin [303], interferon alpha [202,366], etretinate [361], and tumor necrosis factors antagonists (etanercept [392], infliximab [264,278,266], and thalidomide [5,393,425]). Pentoxifylline was postulated to be of therapeutic benefit for treating Sweet's syndrome [394,395]; however, it was not found to be efficacious when used as monotherapy [1,2,7,295,362].…”