2015
DOI: 10.2147/tcrm.s83129
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Testosterone levels of children with a diagnosis of developmental stuttering

Abstract: BackgroundStuttering is defined as a disruption in the rhythm of speech and language articulation, where the subject knows what he/she wants to say, but is unable to utter the intended word or phrase fluently. The effect of sex on development and chronicity of stuttering is well known; it is more common and chronic in males. We aimed to investigate the relationship between developmental stuttering and serum testosterone levels in this study.Materials and methodsIn this study, we evaluated a total of 50 childre… Show more

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Cited by 12 publications
(10 citation statements)
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References 36 publications
(31 reference statements)
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“…Stuttering usually begins between the ages of 2 and 5 years, and it is seen two times further frequently in boys in this age group, while the ratio changes in the adult age group, occurring up to four times more in the male sex because of that T, which is a sex hormone, might play a role in the etiology and chronicity of the disease. T regulates cell death and dopamine transport in the substantia nigra and striatum (Selçuk et al, 2015). It has been shown that changes occurring in the sex steroids during adolescence play an important role in dopamine signaling and regulation (Selçuk et al, 2015).…”
Section: Resultsmentioning
confidence: 99%
“…Stuttering usually begins between the ages of 2 and 5 years, and it is seen two times further frequently in boys in this age group, while the ratio changes in the adult age group, occurring up to four times more in the male sex because of that T, which is a sex hormone, might play a role in the etiology and chronicity of the disease. T regulates cell death and dopamine transport in the substantia nigra and striatum (Selçuk et al, 2015). It has been shown that changes occurring in the sex steroids during adolescence play an important role in dopamine signaling and regulation (Selçuk et al, 2015).…”
Section: Resultsmentioning
confidence: 99%
“…A new trend in the use of AAS is represented by the designer steroids that are not commercially available. Such steroids are designed to be undetectable in tests 13 .…”
Section: Spectrophotometric and Chromatographic Strategies For Explormentioning
confidence: 99%
“…This method is based on the finding that the endogenous steroids and those obtained by chemically show little difference (but detectable) of the carbon isotope ratio of ( 13 C/ 12 C). Chemically obtained steroids are synthesized from certain plant sterols with a low level of 13 C, while the content of 13 C in the human body is higher and reflects the person's diet 19 . During analyze the 13 C/ 12 C ratio for potential administered steroids or their metabolites (androsterone, etiocholanolone, 5α-androstane-3α, 17β-diol, 5β-androstane-3α, 17β-diol) is determinate and compared the 13 C/ 12 C ratio of other endogenic steroids which are not affected by administered steroid (pregnanediol, 11-ketoetiocolonolon) 20 .…”
Section: Spectrophotometric and Chromatographic Strategies For Explormentioning
confidence: 99%
“…3 It is not known why stuttering is more common in males; however, it is thought that this may be associated with prenatal testosterone levels. 4,5 Even though the etiology of developmental stuttering, the most frequent type, has not yet been elucidated, it has been associated with various factors such as atypical neurophysiology, a motor dysfunction in speech, cognitive processing abilities, genetics and environmental impacts. 6,7 Several researchers state that neurological factors play an important role in the etiology of stuttering.…”
mentioning
confidence: 99%