Tannin content of tea and coffee

Savolainen, H.

doi:10.1002/jat.2550120307

Cited by 57 publications

(32 citation statements)

References 10 publications

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“…No correlation was observed between the concentrations of caffeine and tannins in the current samples studied (p = 0.0621). Those levels were higher than that reported by Savolainen (1992) for tannins in coffee samples, at 17-18 g%. Therefore, the tannins levels of the samples confirm the antitoxigenic properties of tannins observed in coffee and tea (Hasan, 1999).…”

Section: Caffeine and Tannins Against Otacontrasting

confidence: 71%

Evaluation of ochratoxin A and fungi in powdered guarana (Paullinia cupana Kunth), a caffeine rich product from Amazon forest

Martins¹,

Kluczkovski²,

Santos³

et al. 2014

Afr. J. Microbiol. Res.

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Guarana (Paullinia cupana Kunth) is a Brazilian commodity well known to stimulate human metabolism due to its alkaloid components (mainly caffeine rich) and is used as an ingredient in the beverage industries. Moreover, the processed form (powdered guarana), may have similarities to other products (coffee, tea and cocoa) regarding its effects on ochratoxin A. This study was to evaluate the effect of the alkaloids of powdered guarana on the OTA production and the toxigenic fungal strains presence, with the specific aim of preventing risks to the consumers and to provide scientific data for those involved in the guarana productions chain. The ochratoxin A levels production of guarana were below the method of LOQ (0.50 µg/kg) and the presence of toxigenic strains was observed only in 2% of the samples. The average level of caffeine was 2.6% (minimum 1.8%; maximum 2.9%) and tannins of 14.7% (minimum 10.0%; maximum 23.1%). The effects of alkaloids from guarana on OTA levels and fungal strains was studied and despite the toxigenic strains were observed in guarana, the OTA levels were below the LOQ (2.0 µg/kg), probably due to the high caffeine content fungi inhibition properties.

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Section: Caffeine and Tannins Against Otacontrasting

confidence: 71%

Evaluation of ochratoxin A and fungi in powdered guarana (Paullinia cupana Kunth), a caffeine rich product from Amazon forest

Martins¹,

Kluczkovski²,

Santos³

et al. 2014

Afr. J. Microbiol. Res.

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“…Tea, for example, contains 40 mg/g TA equivalents, and would require ingestion of 70 g/d to achieve equivalent doses. 21 However, TA is used as a food additive and ingestion of these levels can be achieved by a selective dietary intake. Indeed, TA has been categorized as a generally recognized safe food additive and allowed for use in up to 400 ppm in some foods.…”

Section: Ta Inhibits Growth Of Cholangiocarcinoma Xenograftsmentioning

confidence: 99%

Inhibition of cholangiocarcinoma growth by Tannic acid

Marienfeld

2003

Hepatology

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Cholangiocarcinoma is an aggressive malignancy of the biliary tract for which effective treatment is lacking. Tannic acid (TA) is a naturally occurring polyphenolic compound with antioxidant and radical scavenging properties as well as anticarcinogenic effects. TA inhibited proliferation of malignant human cholangiocytes in vitro. Furthermore, the growth rate of Mz-ChA-1 cholangiocarcinoma xenografts in balb/c athymic mice was reduced from 10.9 ؎ 1.8 mm 3 /d in mice fed with normal water to 5.5 ؎ 1.2 mm 3 /d in mice fed with water containing 0.05% TA. Pretreatment with 50 g/mL TA for 24 hours before xenograft implantation increased tumor latency by 2.5-fold compared with untreated controls, and decreased subsequent growth rates compared with controls in the absence of TA feeding. TA was not cytotoxic to Mz-ChA-1 cells in vitro, but enhanced sensitivity to camptothecin cytotoxicity. TA potently inhibited cell cycle progression, and increased expression of the cyclin-dependent kinase inhibitor p27 KIP1 . In addition, TA (0-50 g/mL) inhibited proteasomal activity in cholangiocyte cell extracts in a concentration-dependent manner. In conclusion, the growth inhibitory effects of TA may result from dysregulation of cell cycle progression due to altered proteasomal degradation of these cell cycle regulatory proteins. TA warrants evaluation as a candidate for the treatment of human cholangiocarcinoma either by itself or in combination with other chemotherapeutic agents. (HEPATOLOGY 2003;37: 1097-1104.)

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“…The problem in most of these studies is that tannic acid is administered in too high doses, which by no means correspond to the ones usually consumed by humans. For example, the content of tannic acid in tea is approximately 40 mg/g of tea (29), which means, according to the studies, that a person should drink the totally unrealistic amount of 250 g of tea extract on a daily basis. Very few studies report the consumption of a quantity of tannic acid that corresponds to 20 g of tea, an amount which is equivalent to the feasible daily consumption of 5 cups of tea (Fig.…”

Section: Tannic Acidmentioning

confidence: 99%

Tannins, xenobiotic metabolism and cancer chemoprevention in experimental animals

Nepka

Asprodini

Kouretas

1999

Eur. J. Drug Metab. Pharmacokinet.

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Tannins are plant polyphenolic compounds that are contained in large quantities in food and beverages (tea, red wine, nuts, etc.) consumed by humans daily. It has been shown that various tannins exert broad cancer chemoprotective activity in a number of animal models. This review summarizes the recent literature regarding both the mechanisms involved, and the specific organ cancer models used in laboratory animals. An increasing body of evidence demonstrates that tannins act as both anti-initiating and antipromoting agents. In view of the fact that tannins may be of valid medicinal efficacy in human clinical trials, the present review attempts to integrate results from animal studies, and considers their possible application in humans.

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Tannin content of tea and coffee

Cited by 57 publications

References 10 publications

Evaluation of ochratoxin A and fungi in powdered guarana (Paullinia cupana Kunth), a caffeine rich product from Amazon forest

Evaluation of ochratoxin A and fungi in powdered guarana (Paullinia cupana Kunth), a caffeine rich product from Amazon forest

Inhibition of cholangiocarcinoma growth by Tannic acid

Tannins, xenobiotic metabolism and cancer chemoprevention in experimental animals

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