Tannins, xenobiotic metabolism and cancer chemoprevention in experimental animals

Nepka, Ch.; Asprodini, Eftihia; Kouretas, Demetrios

doi:10.1007/bf03190367

Cited by 53 publications

(40 citation statements)

References 35 publications

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“…Our findings further support that the antiproliferative tests with the onion root apical meristem cells are correlated with in vivo test using WRBMCs and that was also earlier validated by using other animal cells [44], [45] . The medicinal properties of plants have been claimed to lie in their phytochemical ingredients which can produce a specific action on the human physiology [46][47][48][49][50][51] . The efficient anticancer and anti-neoplastic agents exert their effect through the cell cycle progression machinery [42] .…”

Section: Discussionmentioning

confidence: 99%

Antiproliferative Activity of Allelochemicals Present in Aqueous Extract of Synedrella nodiflora (L.) Gaertn. In Apical Meristems and Wistar Rat Bone Marrow Cells

Ray¹

2013

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Section: Discussionmentioning

confidence: 99%

Antiproliferative Activity of Allelochemicals Present in Aqueous Extract of Synedrella nodiflora (L.) Gaertn. In Apical Meristems and Wistar Rat Bone Marrow Cells

Ray¹

2013

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“…It is distributed widely throughout the world's tropical regions and it has proved difficult to establish its precise origin. The name suggests an Asiatic origin, and other sources (Holm et al, 1977;Kostermans et al, 1987) indicate it originates from the Old World, but Waterhouse (1993) consider it to be of tropical America origin. It occurs as a weed in Africa, the Caribbean region of South America and Central America, tropical regions of North America and southern Asia.…”

Section: Introductionmentioning

confidence: 99%

Proximate, vitamin assays and anti-oxidant properties of an underutilised indigenous vegetable Heliotropium indicum L. (Lamiales: Boraginaceae) in West Africa in enhancing diet diversification

Bello¹,

Amusan²,

Oladeji³

2016

Rev. Bras. Gest. Amb. Sustent.

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Abstract. Green leafy vegetables are important component of human diets, providing fibre, minerals and vitamins. Recently, nonconventional food plants are incorporated in diet to provide not only nutrient but also traditional treatment for various ailments. In a way to combat the devastating effect of malnutrition, there should be a long term intervention such as dietary diversification which can be achieved by increasing the production of locally produced foods and non-conventional vegetables. This study analysed the nutritional composition and anti-oxidant potential of Heliotropium indicum L. (Lamiales: Boraginaceae). The proximate analyses were carried out using the methods described by the Association of Official Analytical Chemist (AOAC). Vitamins were quantified by high performance liquid chromatography (HPLC). Mineral content were determined by Atomic Absorption Spectrophotometric (AAS) technique. The antioxidant activity was tested spectrophotometrically using ascorbic and gallic acid as standards. The nutrient constituents revealed that the fat content ranged between 0.67% ± 0.05% and ash content ranged between 15.7% ± 0.04%. Varying levels of vitamins like ascorbic acid, retinol, tocopherols, riboflavin, thiamine and niacin was quantified in the samples. Ascorbic acid content ranged between 622.6 mg/100 g. The aqueous extracts of the samples significantly (P < 0.05) inhibited DPPH radical with an IC 50 value of 38 μg/mL. It is evident from this study that these indigenous leafy vegetable which are not widely known and consumed are of high nutritional quality and anti-oxidant potential. This vegetable can contribute significantly to the nutrient requirement of man and could complement the conventional ones in enhancing food security and sustainable livelihood. Hence, their cultivation and consumption should be encouraged. incorporadas na dieta para fornecer não só nutrientes, mas também o tratamento tradicional para várias doenças. De forma a combater o efeito devastador da desnutrição, deve haver uma intervenção a longo prazo, como a diversificação da dieta, que pode ser alcançada através do aumento da produção de alimentos produzidos localmente e vegetais não convencionais. Este estudo analisou a composição centesimal e o potencial antioxidante de Heliotropium indicum L. (Lamiales: Boraginaceae). A composição centesimal foi realizada utilizando os métodos descritos pela Associação de Químicos Analíticos Oficiais (AOAC). As vitaminas foram quantificadas por cromatografia líquida de alto desempenho (HPLC). O teor de minerais foi determinado pela técnica de espectrofotometria por absorção atômica (AAS). A atividade anti-oxidante foi testada espectrofotometricamente utilizando ácido ascórbico e ácido gálico como padrões. Os constituintes nutrientes revelaram que o teor de gordura variou entre 0,67 ± 0,05% e o conteúdo de cinzas variou entre 15,7 ± 0,04%. Os níveis variáveis de vitaminas, como ácido ascórbico, retinol, tocoferóis, riboflavina, tiamina e niacina foram quantificados nas amostras. O teor de á...

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“…Tannic acid, which is a commercially important hydrolysable gallotannin, has also got a great deal of attention as an antimicrobial agent due to its antimicrobial, antimutagenic, anticarcinogenic and antioxidant properties [1, 3,4,10,22,23,31,35,37,41,44]. Tannic acid is present in a variety of fruits and vegetables including tea, cocoa, beans, grapes, strawberry, persimmon, especially the bark of the oak species, sumac and myrobalan [1, 11,40] and also categorized as a 'generally recognized as safe' (GRAS) food additive [1]. In addition, it is not classifi ed as hazardous material according to CLP Regulation (EC) 1272/2008 on classifi cation, labeling and packaging of substances and mixtures [32].…”

Section: Introductionmentioning

confidence: 99%

Eco-Friendly Soaking Process Using Tannic Acid as an Alternative Bactericide

Zengin¹,

Çolak²,

Zengin³

et al. 2014

Archives of Environmental Protection

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Eco-friendly leather processes based on the usage of natural products have become a potentially attractive issue for leather industry during the last few decades. Synthetic protective chemicals like bactericides used in most soaking process are known as hazardous substances and cause tannery effl uents with high concentrations of Chemical Oxygen Demand (COD). In the present study, the effect of tannic acid on microorganisms, skin, wool and effl uent were investigated in order to demonstrate the applicability of tannic acid in soaking process instead of commonly used bactericides. The bacterial load (cfu/ml), COD and Nitrogen Content (N) of the soaking effl uents and Total Kjeldahl Nitrogen (TKN) content of skins and wools were investigated. Application of 0.5 and 1 wt% tannic acid concentrations was more effective than commercial bactericide, while comparable results were achieved by 0.1 and 0.3 wt% tannic acid. The application of tannic acid for soaking process resulted in lower COD and N values of effl uents. The results show that tannic acid has the potential to be an alternative, eco-friendly bactericide for leather industry by reducing the pollution of leather soaking process.

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Tannins, xenobiotic metabolism and cancer chemoprevention in experimental animals

Cited by 53 publications

References 35 publications

Antiproliferative Activity of Allelochemicals Present in Aqueous Extract of Synedrella nodiflora (L.) Gaertn. In Apical Meristems and Wistar Rat Bone Marrow Cells

Antiproliferative Activity of Allelochemicals Present in Aqueous Extract of Synedrella nodiflora (L.) Gaertn. In Apical Meristems and Wistar Rat Bone Marrow Cells

Proximate, vitamin assays and anti-oxidant properties of an underutilised indigenous vegetable Heliotropium indicum L. (Lamiales: Boraginaceae) in West Africa in enhancing diet diversification

Eco-Friendly Soaking Process Using Tannic Acid as an Alternative Bactericide

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