Tannic Acid with Antiviral and Antibacterial Activity as A Promising Component of Biomaterials—A Minireview

Kaczmarek, Beata

doi:10.3390/ma13143224

Cited by 333 publications

(259 citation statements)

References 68 publications

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“…The study of tannic acid released from collagen-tannic acid complexes suggests that it has a killing effect for microbes which are not cytotoxic to human cells. The addition of tannic acid to collagen significantly decreases its hydrolysis rate and affects the antioxidant properties [103]. As tannic acid interacts with collagen by forming hydrogen bonds, it is released to the surrounding environment.…”

Section: Collagen-tannic Acidmentioning

confidence: 99%

Collagen-Based Materials Modified by Phenolic Acids—A Review

Kaczmarek

Mazur

2020

Materials

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Collagen-based biomaterials constitute one of the most widely studied types of materials for biomedical applications. Low thermal and mechanical parameters are the main disadvantages of such structures. Moreover, they present low stability in the case of degradation by collagenase. To improve the properties of collagen-based materials, different types of cross-linkers have been researched. In recent years, phenolic acids have been studied as collagen modifiers. Mainly, tannic acid has been tested for collagen modification as it interacts with a polymeric chain by strong hydrogen bonds. When compared to pure collagen, such complexes show both antimicrobial activity and improved physicochemical properties. Less research reporting on other phenolic acids has been published. This review is a summary of the present knowledge about phenolic acids (e.g., tannic, ferulic, gallic, and caffeic acid) application as collagen cross-linkers. The studies concerning collagen-based materials with phenolic acids are summarized and discussed.

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Section: Collagen-tannic Acidmentioning

confidence: 99%

Collagen-Based Materials Modified by Phenolic Acids—A Review

Kaczmarek

Mazur

2020

Materials

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“…Scarceness of iron has an important impact on microorganisms, as it is essential for several metabolic processes involved in bacterial replication, growth and virulence ( Doherty, 2007 ). Other studies suggest that TA might cause bacterial cell wall disruption as a result of TA complexation with enzymes and substrates located on the outer cell membrane ( Akiyama et al, 2001 ; Kaczmarek, 2020 ). 3D in vitro evaluation of the antibacterial effectiveness of coated scaffolds against S. aureus in suspension evidenced the synergistic antibacterial effect of HSA and TA.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction

Cometta

Bock

Suresh

et al. 2021

Front. Bioeng. Biotechnol.

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Infection is the major cause of morbidity after breast implant surgery. Biodegradable medical-grade polycaprolactone (mPCL) scaffolds designed and rooted in evidence-based research offer a promising alternative to overcome the limitations of routinely used silicone implants for breast reconstruction. Nevertheless, as with any implant, biodegradable scaffolds are susceptible to bacterial infection too, especially as bacteria can rapidly colonize the biomaterial surface and form biofilms. Biofilm-related infections are notoriously challenging to treat and can lead to chronic infection and persisting inflammation of surrounding tissue. To date, no clinical solution that allows to efficiently prevent bacterial infection while promoting correct implant integration, has been developed. In this study, we demonstrated for the first time, to our knowledge that the physical immobilization of 1 and 5% human serum albumin (HSA) onto the surface of 3D printed macro- and microporous mPCL scaffolds, resulted in a reduction of Staphylococcus aureus colonization by 71.7 ± 13.6% and 54.3 ± 12.8%, respectively. Notably, when treatment of scaffolds with HSA was followed by tannic acid (TA) crosslinking/stabilization, uniform and stable coatings with improved antibacterial activity were obtained. The HSA/TA-coated scaffolds were shown to be stable when incubated at physiological conditions in cell culture media for 7 days. Moreover, they were capable of inhibiting the growth of S. aureus and Pseudomonas aeruginosa, two most commonly found bacteria in breast implant infections. Most importantly, 1%HSA/10%TA- and 5%HSA/1%TA-coated scaffolds were able to reduce S. aureus colonization on the mPCL surface, by 99.8 ± 0.1% and 98.8 ± 0.6%, respectively, in comparison to the non-coated control specimens. This system offers a new biomaterial strategy to effectively translate the prevention of biofilm-related infections on implant surfaces without relying on the use of prophylactic antibiotic treatment.

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“…Of particular interest are silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) for their activities against viral infections, including HIV (AgNPs, glucose-coated AuNPs, AuNPs conjugated with peptide triazoles, sulfated ligands-coated AuNPs, fluorescein-labeled oligomannoside AuNPs, mercaptobenzoic acid-coated AuNPs, and quantum rods), HBV (solid lipid nanoparticles), HSV-1 (PVP-stabilized AgNPs, mercaptoethanesulfonate-capped AgNPs, and mercaptoethane sulfonate-capped AuNPs), HPV (PVP-stabilized AgNPs), H1N1 influenza (AgNPs/chitosan composites), and Tacaribe virus (polysaccharide-coated AgNPs). In addition to these nanomaterials, tannic acid is a naturally driven phenolic acid that provides defense against influenza A virus, papillomaviruses, noroviruses, HSV, and HIV [173].…”

Section: Biomaterials For Potential Anti-viral Activitymentioning

confidence: 99%

Biosensing surfaces and therapeutic biomaterials for the central nervous system in COVID-19

Saghazadeh

Rezaei

2021

emergent mater.

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COVID-19 can affect the central nervous system (CNS) indirectly by inflammatory mechanisms and even directly enter the CNS. Thereby, COVID-19 can evoke a range of neurosensory conditions belonging to infectious, inflammatory, demyelinating, and degenerative classes. A broad range of non-specific options, including anti-viral agents and anti-inflammatory protocols, is available with varying therapeutic. Due to the high mortality and morbidity in COVID-19–related brain damage, some changes to these general protocols, however, are necessary for ensuring the delivery of therapeutic(s) to the specific components of the CNS to meet their specific requirements. The biomaterials approach permits crossing the blood–brain barrier (BBB) and drug delivery in a more accurate and sustained manner. Beyond the BBB, drugs can protect neural cells, stimulate endogenous stem cells, and induce plasticity more effectively. Biomaterials for cell delivery exist, providing an efficient tool to improve cell retention, survival, differentiation, and integration. This paper will review the potentials of the biomaterials approach for the damaged CNS in COVID-19. It mainly includes biomaterials for promoting synaptic plasticity and modulation of inflammation in the post-stroke brain, extracellular vesicles, exosomes, and conductive biomaterials to facilitate neural regeneration, and artificial nerve conduits for treatment of neuropathies. Also, biosensing surfaces applicable to the first sensory interface between the host and the virus that encourage the generation of accelerated anti-viral immunity theoretically offer hope in solving COVID-19.

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Tannic Acid with Antiviral and Antibacterial Activity as A Promising Component of Biomaterials—A Minireview

Cited by 333 publications

References 68 publications

Collagen-Based Materials Modified by Phenolic Acids—A Review

Collagen-Based Materials Modified by Phenolic Acids—A Review

Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction

Biosensing surfaces and therapeutic biomaterials for the central nervous system in COVID-19

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