Tailoring, physicochemical characterization, antibacterial and DNA binding mode studies of Cu(II) Schiff bases amino acid bioactive agents incorporating 5-bromo-2-hydroxybenzaldehyde

Abu‐Dief, Ahmed M.; Nassr, Lobna A. E.

doi:10.1007/s13738-014-0557-9

Cited by 116 publications

(89 citation statements)

References 40 publications

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“…The ligand and metal complexes were screened for antimicrobial activity and were compared with Rifampicin (an active against antimicrobial agent against Gram-negative and Gram-positive bacterial strains). The synthesized compounds exhibited significant activities versus standard antimicrobial agents, and these findings are in line with reported studies that the metal complexes can exhibit higher antimicrobial/antibacterial activity than the parent ligands [44][45][46][47][48]. At higher concentrations the complexes (1-5) exhibited considerable antibacterial activity against E. coli, P. multosida, and S. aerues.…”

Section: Resultssupporting

confidence: 86%

Cytotoxicity and Antimicrobial Activity of Pivalic and Benzoic Acid-Complexed Cu and Mn Complexes

Ali¹,

Tahir²,

Akhtar³

et al. 2017

Pol. J. Environ. Stud.

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Section: Resultssupporting

confidence: 86%

Cytotoxicity and Antimicrobial Activity of Pivalic and Benzoic Acid-Complexed Cu and Mn Complexes

Ali¹,

Tahir²,

Akhtar³

et al. 2017

Pol. J. Environ. Stud.

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“…Melting points of the prepared ligands and decomposition temperatures of their copper complexes were determined using a Gallenkamp (UK) apparatus. NMR spectra of the ligands were recorded in Bruker ARX at 400.1 ( 1 H) and 100.6 ( 13 C) MHz using DMSO-d 6 . A Perkin-Elmer 240c Elemental analyzer was used to micro-analytical data (C, H and N).…”

Section: Physical Measurementsmentioning

confidence: 99%

“…Schiff base transition metal complex derivatives are the most attractive oxidation catalysts for alcohols and alkenes because of their cheap, easy synthesis, their chemical and thermal stability. Various studies have shown that the azomethine group have alone pair of electrons in either p or sp 2 hybridized orbital on nitrogen has biological and catalytic importance [6,7]. Copper is copious metal on the earth's crust and is found in Electronic supplementary material The online version of this article (doi:10.1007/s10562-016-1755-0) contains supplementary material, which is available to authorized users.…”

Section: Introductionmentioning

confidence: 99%

Some New Nano-sized Mononuclear Cu(II) Schiff Base Complexes: Design, Characterization, Molecular Modeling and Catalytic Potentials in Benzyl Alcohol Oxidation

et al. 2016

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In the present contribution, some novel Cu(II) complexes were synthesized from tri-and tetradentate imine ligands. All the prepared compounds were elucidated by different physicochemical methods. Density Functional Theory calculations were carried out to explain the equilibrium geometry of the bsisnph and npisnph ligands and their Cu(II) complexes. Interaction of the synthesized ligands with Cu(II) affords nano-sized particles via TEM. The catalytic potentials of the prepared complexes has been tested within the oxidation of benzyl alcohol using an environmental friendly terminal oxidant, i.e. H 2 O 2 . The effect of various parameters, e.g. solvents, temperature and amount of catalyst was investigated. A mechanistic pathway of the catalytic oxidation was tentatively described and discussed. Graphical AbstractKeywords Cu(II) Schiff base complexes · TEM · Benzyl alcohol · Density Functional Theory · Catalytic activity · Hydrogen peroxide

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“…This is because on chelation, the polarity of the metal ion will be reduced due to the overlap of the ligand orbital and partial sharing of the positive charge of the metal ion with donor groups and possibly electron delocalization over the whole molecule [40][41][42]. This may enhance the penetration of the complex into the lipid membranes enabling it to block the metal binding sites in the enzymes of microorganisms.…”

Section: Applications Antibacterial Activity Of Complexes In Agar Mediummentioning

confidence: 99%

Synthesis of Co(II) and Cr(III) salicylidenic Schiff base complexes derived from thiourea as precursors for nano-sized Co3O4 and Cr2O3 and their catalytic, antibacterial properties

Kafi‐Ahmadi

Shirmohammadzadeh

2017

J Nanostruct Chem

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This study focuses on the synthesis of Co(II) and Cr(III) Schiff base complexes obtained from thiourea. The complexes were synthesized by template method and characterized by elemental analysis (CHNS), FT-IR, UVvis spectroscopy, conductivity measurement and magnetic moment. The spectroscopic studies suggested the octahedral and square-pyramidal structures for Co(II) and Cr(III) complexes, respectively. Then the complexes were used as precursors for preparation of Co 3 O 4 and Cr 2 O 3 nanoparticles via solid-state thermal decomposition without using a catalyst, toxic solvent, template or surfactant and complicated equipment, which makes it efficient, one-step, simple and environment-friendly. The chemical structure of the metal oxides is studied by FT-IR, XRD and SEM. To investigate the applications of the synthesized complexes, in the next step, the complexes were screened for antibacterial activity against clinically important bacteria such as Escherichia coli, Staphylococcus aureus, and Bacillus subtilis. The Cr(III) and Co(II) complexes showed good biological activity against all the tested bacteria. Also, the catalytic activities of the complexes were studied in toluene using non-toxic hydrogen peroxide as the oxidant. The results showed that Co(II) complex has catalytic activity for oxidation of toluene, but Cr(III) complex did not show any catalytic activity.

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Tailoring, physicochemical characterization, antibacterial and DNA binding mode studies of Cu(II) Schiff bases amino acid bioactive agents incorporating 5-bromo-2-hydroxybenzaldehyde

Cited by 116 publications

References 40 publications

Cytotoxicity and Antimicrobial Activity of Pivalic and Benzoic Acid-Complexed Cu and Mn Complexes

Cytotoxicity and Antimicrobial Activity of Pivalic and Benzoic Acid-Complexed Cu and Mn Complexes

Some New Nano-sized Mononuclear Cu(II) Schiff Base Complexes: Design, Characterization, Molecular Modeling and Catalytic Potentials in Benzyl Alcohol Oxidation

Synthesis of Co(II) and Cr(III) salicylidenic Schiff base complexes derived from thiourea as precursors for nano-sized Co3O4 and Cr2O3 and their catalytic, antibacterial properties

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