1972
DOI: 10.1016/s0140-6736(72)92650-5
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T3 Toxicosis in an Iodine-Deficient Area

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Cited by 38 publications
(13 citation statements)
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“…Aizawa et al reporting on 536 GD patients also found lower T 3 and T 4 concentrations among elderly patients. Several studies have reported a connection between iodine intake and the prevalence of T 3 and T 4 toxicosis, the former being more prevalent in iodine-deficient areas (4,32) and the latter dominating in areas with a higher iodine intake (33). We found that T 4 was higher in GD and MNTG patients diagnosed in the region with the highest iodine intake.…”
Section: Determinants For Hormonal Levels In Gd Mntg and Stasupporting
confidence: 49%
“…Aizawa et al reporting on 536 GD patients also found lower T 3 and T 4 concentrations among elderly patients. Several studies have reported a connection between iodine intake and the prevalence of T 3 and T 4 toxicosis, the former being more prevalent in iodine-deficient areas (4,32) and the latter dominating in areas with a higher iodine intake (33). We found that T 4 was higher in GD and MNTG patients diagnosed in the region with the highest iodine intake.…”
Section: Determinants For Hormonal Levels In Gd Mntg and Stasupporting
confidence: 49%
“…These findings suggest that the frequency of T3 toxicosis is significantly higher in areas of iodine deficiency (Hollander et al, 1972). Studies have shown the persistence of moderate or even severely affected areas of iodine deficite in several countries of Eastern Europe and in Baltic States (Vitti et al, 2001).…”
Section: Discussionmentioning
confidence: 83%
“…However, ATD is known to cause an intrathyroidal iodine deficiency (Studer and Greer, 1967) with the preferential synthesis of MIT rather than DIT (Richards andIngbar, 1959 Slingerland et at., 1959) and, preferential secretion of T3 rather than T4 (Bellabarba et al, 1972;Hollander et al, 1972). Abuid and Larsen (1974) reported that PTU decreased the T3 level more than MMI in the acute phase, since PTU inhibited both pathways for T3 production.…”
Section: Discussionmentioning
confidence: 99%