Syndrome of isolated FT3 toxicosis: A pilot study

Abstract

When free thyroxine (FT4) concentration is elevated and thyrotropin (TSH) concentrarion is

Atezolizumab-Induced Hypothyroidism in a Patient With Pre-existing Triiodothyronine (T3) Thyrotoxicosis Due to Graves’ Disease: A Case Report and Literature Review

“…This accounts for approximately 5% of cases of thyrotoxicosis. T3-thyrotoxicosis is caused by iodine deficiency or compensatory increased hormone production or faster peripheral T4 to T3 conversion or increased hormone production in patients with Graves’ disease, single toxic nodule or multinodular disease [ 14 ]. Graves’ disease is treated by decreasing thyroid hormone synthesis with the use of anti-thyroid drugs or by reducing the amount of thyroid tissue with radioactive iodine treatment or total thyroidectomy.…”

Elevation of free triiodothyronine (fT3) levels by Plasmodium falciparum independent of thyroid stimulating hormone (TSH) in children with uncomplicated malaria

“…Isolated fT3 thyrotoxicosis is observed in conditions where fT4 and TSH levels are in the normal human range with elevated fT3 level. 44 In contrast to publication by, 41 the mean level of fT3 observed in the malaria cases was above the normal Ghanaian level of 2.73–4.13 pmol/L. 45 In isolated fT3 thyrotoxicosis, fatigue, lethargy, and weight loss have been reported, 46 clinical presentations that are commonly observed in about 74% of children with malaria.…”

“…According to the findings of this study, thyroid hormone levels in relation to P. falciparum infection were consistent with isolated fT3 thyrotoxicosis. Isolated fT3 thyrotoxicosis is observed in conditions where fT4 and TSH levels are in the normal human range with elevated fT3 level 44 . In contrast to publication by, 41 the mean level of fT3 observed in the malaria cases was above the normal Ghanaian level of 2.73–4.13 pmol/L 45 .…”