T2*-Weighted and Arterial Spin Labeling MRI of Calf Muscles in Healthy Volunteers and Patients With Chronic Exertional Compartment Syndrome: Preliminary Experience

Abstract

After calf muscle exercise, no statistically significant differences in T2* relaxation times or arterial spin labeling signal, indicative of differences in muscle oxygenation and perfusion status, were found between patients with chronic exertional compartment syndrome and control subjects.

MR Imaging of Muscle Trauma: Anatomy, Biomechanics, Pathophysiology, and Imaging Appearance

“…However, the specificity of imaging is not yet established. Andreisek et al (58) performed T2*-weighted and arterial spin labeling imaging after exercise and noted identical transient changes in asymptomatic volunteers and patients with CECS, although the latter group reported greater fatigue and pain.…”

“…Chronic exertional compartment syndrome (CECS) causes aching pain, cramping, and muscle tightness during exercise, typically of the anterior or lateral calf, and is often bilateral (58). Symptoms typically resolve rapidly after cessation of activity without structural damage, although rarely extreme cases can progress to acute compartment syndrome.…”

“…Increased muscle signal intensity on fluid-sensitive images may be accompanied by muscle swelling and fascial edema; these alterations, identical to those after vigorous concentric contraction, are maximal immediately after exercise and resolve within 30 minutes (Fig 29). Quantitative T2 measurement, spectroscopy, and functional MR imaging afford even higher sensitivity (14,58,60,62). However, the specificity of imaging is not yet established.…”

Skeletal muscle quantitative nuclear magnetic resonance imaging and spectroscopy as an outcome measure for clinical trials (part II)

“…Несколько состояний, влияющих на скелетные мышцы, были исследованы с помощью функциональ-ной томографии, в частности острая и хроническая ишемия [149][150][151][152], диабет [153], прогрессирующий системный склероз (склеродермия) [154] и синдром длительного сдавления [155].…”

Imagerie et spectroscopie par résonance magnétique nucléaire du muscle strié squelettique

“…Dans sa décli-naison RMN totalement atraumatique, la perfusion est déterminée par ASL, et le taux d'oxygénation des gros vaisseaux est obtenu par des mesures de T2 ou de susceptibilité (Zheng et al 2013 ;Englund et al 2013 ;Decorte et al 2014). Différentes conditions qui affectent la perfusion et l'oxygénation du muscle squelettique ont été étu-diées par la RMN fonctionnelle, en particulier l'ischémie aiguë ou chronique (Ledermann et al 2006 ;Grözinger et al 2013 ;Aschwanden et al 2014 ;Englund et al 2015), mais également le diabète (Zheng et al 2014), la sclérose systémique ) ou encore le syndrome des loges (Andreisek et al 2009). En ce qui concerne les pathologies neuromusculaires, l'emploi de l'imagerie fonctionnelle par RMN a été jusqu'à présent très limité.…”