T. Duckett Jones and rheumatic fever in 1986. T. Duckett Jones Memorial Lecture.

Denny, Floyd W.

doi:10.1161/01.cir.76.5.963

Cited by 40 publications

(5 citation statements)

References 10 publications

(2 reference statements)

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“…Three percent of patients with untreated group A β-hemolytic streptococcus (GAS) pharyngitis developed RF,27 and subsequent or recurrent GAS pharyngitis increases the risk of RF from 3% to 75% 28. A study in Benin City, Nigeria, showed a streptococcal throat colonization prevalence rate of 9.7% from groups C, G, B, and F, and not colonization with GAS 29.…”

Section: Discussionmentioning

confidence: 99%

The new face of rheumatic heart disease in South West Nigeria

Akinwusi

Peter

Oyedeji³

et al. 2013

IJGM

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PurposeTo determine the current prevalence of rheumatic heart disease (RHD), clinical features, types of valvular lesions, complications and mortality, at Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital, Osogbo, South West Nigeria.MethodsWe conducted a retrospective, descriptive study of all the cases of RHD seen in the medical outpatient clinics and wards of LAUTECH for 9 years, from January 2003 to December 2011. Statistical analysis of data obtained was done using SPSS 16.ResultsThe total number of attendees of all the medical outpatient clinics during the 9-year period was 67,378, with a subset of 9423 attending the cardiology clinic. There were 11 cases of RHD, which translates to a prevalence of 0.16/1000 and 1.2/1000 for medical outpatient clinics and the cardiology clinic respectively. The mean age of the patients was 25.64 ± 9.65 years, age range 14–40 years and male to female ratio of 1:1.2. The most common valve affected was mitral (90.9%), followed by the aortic (36.4%), and the tricuspid (18.2%). Mitral and aortic lesions coexisted in 18.2% of the patients, and late presentation was common in all RHD cases. Heart failure was the most common complication (90.9%). Other complications were secondary pulmonary hypertension (36.4%), infective endocarditis (27.3%), atrial fibrillation (27.3%), cardioembolic cerebrovascular disease (18.2%), and atrial flutter (9.1%). Mortality was 9.1%, while only one patient (9.1%) had definitive surgery. Financial constraints precluded others from having definitive surgery.ConclusionThe prevalence of RHD has declined considerably as a result of improvements in the primary health care delivery system, with widespread use of appropriate antibiotic therapy for sore throats resulting in the prevention of rheumatic fever and RHD. However, late presentation is still very common, hence we advocate a more aggressive drive to make the Drakensberg declaration on the control of rheumatic fever and rheumatic heart disease functional in our practice area.

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Section: Discussionmentioning

confidence: 99%

The new face of rheumatic heart disease in South West Nigeria

Akinwusi

Peter

Oyedeji³

et al. 2013

IJGM

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“…The link between acute RF and GABHS pharyngitis has been established firmly by observational and experimental data in Western countries 7 9 – 13. Three per cent of GABHS pharyngitis leads to RF if left untreated,14 but the risk of RF increases from 3% to 75% after subsequent or recurrent GABHS pharyngitis 15 – 17. GABHS pharyngitis represents 20% of all pharyngitis with symptoms of fever and sore throat and affects principally children and young adults, most commonly in the age group 5–15 years 18.…”

Section: Aetiology Of Rheumatic Fevermentioning

confidence: 97%

Epidemiology and prevention of valvular heart diseases and infective endocarditis in Africa

Nkomo

2006

Heart

107

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“…По выражению аме-риканского ревматолога F.W.Denny, «мы воспитали целое поколение врачей, которые не знают острой рев-матической лихорадки» [12]. Однако вопросы свое-временной и точной ее диагностики по-прежнему со-храняют свою значимость.…”

Section: Discussionunclassified