Systemic Photodynamic Therapy Is a Safe and Effective Treatment for Psoriasis

Boehncke, Wolf‐Henning; Elshorst-Schmidt, Thomas; Kaufmann, Roland

doi:10.1001/archderm.136.2.271

Cited by 65 publications

(36 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…PDT is also valuable for premalignant conditions such as oral leukoplakia, mucosal dysplasia, or carcinoma in situ [21]. It has also been used for nononcologic purposes like psoriasis [6,7].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Methylene blue‐mediated photodynamic therapy: A possible alternative treatment for oral lichen planus

et al. 2006

View full text Add to dashboard Cite

Background and Objectives: In this study, methylene blue-mediated photodynamic therapy (MB-PDT) was used as a possible alternative method for the treatment of oral lichen planus (OLP). Study Design/Materials and Methods: Thirteen patients with 26 OLP lesions were enrolled in this study. Patients were instructed to gargle a 5% methylene blue solution in water for 5 minutes. Ten minutes later, irradiation was performed by laser light (l ¼ 632 nm, light exposure dose ¼ 120 J/cm 2 ). Lesions were evaluated pre and post-operatively and at follow-up sessions by changes in sign and symptom (pain) scores, and size of lesions. Results: Improvement in sign scores was achieved in 16 lesions. Four keratotic lesions disappeared completely. There was a statistically significant decrease in sign and symptom scores 1 week after treatment and at follow-up sessions up to 12 weeks. Average reduction in size of lesions was 44.3%. Conclusion: MB-PDT seems to be an effective alternative treatment for control of OLP. In our opinion, this preliminary result warrant further studies in order to show the efficacy of MB-PDT in control of OLP for a longer period of time.

show abstract

Section: Discussionmentioning

confidence: 99%

“…It has also been used for non-oncologic purposes like psoriasis [6,7]. PDT involves in situ photo-activation of photosensitizers (PSs) by light at appropriate wavelength, generating highly active and short-lived oxygen derived species [8].…”

Section: Introductionmentioning

confidence: 99%

Methylene blue‐mediated photodynamic therapy: A possible alternative treatment for oral lichen planus

et al. 2006

View full text Add to dashboard Cite

show abstract

“…PDT has been administered not only for malignant skin tumors but also for benign inflammatory or infectious skin lesions, including psoriasis vulgaris [11, 12], acne vulgaris [13], and various types of warts [14,15,16]. In this report, we present evidence that topical PDT with ALA leads to successful treatment of benign lymphoid hyperplasia of LABC.…”

Section: Discussionmentioning

confidence: 86%

Successful Treatment of Lymphadenosis benigna cutis with Topical Photodynamic Therapy with Delta-Aminolevulinic Acid

Takeda¹,

Kaneko²,

Harada³

et al. 2005

Dermatology

View full text Add to dashboard Cite

Background: Photodynamic therapy (PDT) using topical δ-aminolevulinic acid (ALA) has been used for nonmelanoma skin cancers, including malignant cutaneous T-cell lymphomas. Moreover, PDT has been tried for benign inflammatory or infectious skin lesions. Objective: To evaluate the effects of ALA-PDT on skin lesions of lymphadenosis benigna cutis (LABC). Patients and Methods: Two 16-year-old females with solitary and infiltrated nodules were treated 5 times with topical ALA-PDT. Results: Both patients responded well and showed dramatic clinical and histopathological improvement without visible scars. Conclusion: The results confirm that topical ALA-PDT is an effective and safe modality for the treatment of LABC, and that such treatment may be cosmetically beneficial.

show abstract

“…Until now, topical ALA-PDT has been successfully used for the management of superficial skin tumors such as basal cell carcinoma, Bowen's disease, and actinic keratoses. 12 Inflammatory diseases of the skin, such as psoriasis and localized scleroderma, 13,14 and human papillomavirus-induced dermatoses, including condyloma acuminatum, epidermodysplasia verruciformis, and verruca vulgaris, [15][16][17] respond positively to ALA-PDT. However, to our knowledge PDT has not been described for the treatment of granulomatous skin disorders affecting the dermis.…”

Section: Commentmentioning

confidence: 99%

Successful Treatment of Cutaneous Sarcoidosis Using Topical Photodynamic Therapy

Karrer

Abels²,

Wimmershoff³

et al. 2002

Arch Dermatol

View full text Add to dashboard Cite

Systemic Photodynamic Therapy Is a Safe and Effective Treatment for Psoriasis

Cited by 65 publications

References 4 publications

Methylene blue‐mediated photodynamic therapy: A possible alternative treatment for oral lichen planus

Methylene blue‐mediated photodynamic therapy: A possible alternative treatment for oral lichen planus

Successful Treatment of Lymphadenosis benigna cutis with Topical Photodynamic Therapy with Delta-Aminolevulinic Acid

Successful Treatment of Cutaneous Sarcoidosis Using Topical Photodynamic Therapy

Contact Info

Product

Resources

About