2001
DOI: 10.1006/bbrc.2001.5414
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Systematic Search for Single Nucleotide Polymorphisms in the Insulin Gene: Evidence for a High Frequency of −23T→A in Japanese Subjects

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Cited by 10 publications
(5 citation statements)
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“…Previous studies including this one showed the allele and genotype of the VNTR polymorphism in INS gene were different among ethical populations. Osawa et al found the A allele frequency of -23/HphI polymorphism was 97.4% in Japanese subjects, whereas in Europeans it was about 30% [18]. The results in this study showed the A allele frequency was about 93.5% (Table 2).…”
Section: Discussionsupporting
confidence: 47%
“…Previous studies including this one showed the allele and genotype of the VNTR polymorphism in INS gene were different among ethical populations. Osawa et al found the A allele frequency of -23/HphI polymorphism was 97.4% in Japanese subjects, whereas in Europeans it was about 30% [18]. The results in this study showed the A allele frequency was about 93.5% (Table 2).…”
Section: Discussionsupporting
confidence: 47%
“…PCR direct sequencing was performed as described previously with the following modifications (13,14). Genomic DNA was extracted from leukocytes using a DNA Isolation Kit for Mammalian Blood (Boehringer Mannheim, Indianapolis, IN).…”
Section: Methodsmentioning
confidence: 99%
“…PCR direct sequencing was performed as described previously (11,12). Genomic DNA was extracted from leukocytes using a DNA Isolation Kit for Mammalian Blood (Boehringer Mannheim, Indianapolis, IN).…”
Section: Methodsmentioning
confidence: 99%