Synthesis, structure and spectroscopic studies on DNA binding, BSA interaction of a nickel(II) complex containing<scp>l</scp>–methionine Schiff base and 1,10-phenanthroline

Zhao, Peiran; Wei, Qiang; Ding, Feifei; Li, Jinghong; Li, Lianzhi

doi:10.1080/00958972.2016.1206657

Cited by 21 publications

(1 citation statement)

References 74 publications

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“…BSA is generally selected as a target protein due to its low cost and similarity to human serum albumin (HSA) [12]. Previously, DNA and BSA-binding properties of metal-based Schiff base complexes were investigated by Wei's [13][14][15] and Guo's groups [16][17][18]. For example, two hexacoordinated octahedral nickel (II) complexes [14] of Schiff bases derived from o-vanillin/salicylaldehyde with glutamine and an Ni(II) complex [15] of Schiff base of o-vanillin and l-methionine in the presence of 1,10-phenanthroline were synthesized and characterized.…”

Section: Introductionmentioning

confidence: 99%

Pt(II) complex of Schiff base derived from L-phenylalanine and furfuraldehyde in the presence of 8-hydroxyquinoline: Structural analysis, composition of complex and biological activity

Altun¹,

Koçer²

2020

Comptes Rendus. Chimie

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In the present study, we synthesized a Schiff base (L 1) derived from L-phenylalanine with furfuraldehyde and its Pt(II) complex ([Pt(L 1)(L 2)]: [Pt(N-(furfuralidene)phenylalanine)(8hydroxyquinoline)]) in the presence of 8-hydroxyquinoline (L 2). The chemical structures of the synthesized Schiff base and Pt(II) complex were characterized using ESI-MS, UV-Visible, FT-IR, 1 H NMR, 13 C NMR, and powder-XRD spectroscopy. The surface morphologies and elemental composition were determined by SEM and EDX. Thermal analysis was performed with TG-DTA. Mole ratio of Meyer and Job methods were used for the composition of complexes. According to these methods, the ratio [Pt 2+ ] : [L 1 + L 2 ] was found to be 1 : 1. In addition, the antimicrobial activities of L 1 and the complex showed that the compounds have significant antibacterial and antifungal properties. They also show important cytotoxic effects against the growth of mouse embryo fibroblasts (MEF) and human prostate adenocarcinoma (Du145) cancer cells. L 1 , L 2 , and the Pt(II) complex also displayed effective antioxidant activity.

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Section: Introductionmentioning

confidence: 99%

Pt(II) complex of Schiff base derived from L-phenylalanine and furfuraldehyde in the presence of 8-hydroxyquinoline: Structural analysis, composition of complex and biological activity

Altun¹,

Koçer²

2020

Comptes Rendus. Chimie

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Thioether and Chiral S chiff Base

Singh

Gogoi

Barman

2023

Schiff Base Metal Complexes

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Supramolecular interaction of transition metal complexes with albumins and DNA: Spectroscopic methods of estimation of binding parameters

Galkina

Проскурнин

2018

Applied Organom Chemis

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Binding parameters of metal complexes with albumins and DNA since the middle of 1990s are considered and summarized. The most widespread spectroscopic methods of estimation of binding parameters are discusseddirect fluorescent methods, indirect fluorescent methods (by fluorescence quenching parameters), and ways of estimation of binding constants by other optical spectroscopic methods. The methods and approaches to calculations used for the determination of binding constants are discussed. The data on the already found binding constants and kinetic parameters is systematized.KEYWORDS albumins, DNA, metal complexes, proteins, supramolecular interaction Funding information: Russian Foundation for Basic Research, Grant/Award Number: 16-03-01089_a 16-53-50027_YaF_a Abbreviations and designations used: F 0 , fluorescence intensity in the absence of a quencher; F, fluorescence intensity in the presence of a acid); NTSC, a new thiosemicarbazone; o-cbiaH, 5-(2-carboxybenzyloxy)isophthalic acid; o-van-gln, a Schiff base derived from o-vanillin and glutamine; o-van-L-met, Schiff base derived from o-vanillin and L-methionine; oxo, 5-

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Synthesis, structure and spectroscopic studies on DNA binding, BSA interaction of a nickel(II) complex containingl–methionine Schiff base and 1,10-phenanthroline

Cited by 21 publications

References 74 publications

Pt(II) complex of Schiff base derived from L-phenylalanine and furfuraldehyde in the presence of 8-hydroxyquinoline: Structural analysis, composition of complex and biological activity

Pt(II) complex of Schiff base derived from L-phenylalanine and furfuraldehyde in the presence of 8-hydroxyquinoline: Structural analysis, composition of complex and biological activity

Thioether and Chiral S chiff Base

Supramolecular interaction of transition metal complexes with albumins and DNA: Spectroscopic methods of estimation of binding parameters

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