Synthesis, structural and biomedical characterization of hydroxyapatite/borosilicate bioactive glass nanocomposites

Abstract

In this work, a borosilicate glass sample (5SiO2-45B2O3-20Na2O-25CaO-5Ag2O) was added to nano-sized carbonated hydroxyapatite (CHA) powders with different contents up to 20 wt.% to improve the bioactivity, antibacterial effect, physical and mechanical properties of the resulting nanocomposites. Then, these samples were mixed, milled with a high-energy ball mill, sintered at 700°C and subjected to X-ray diffraction (XRD) technique, Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) to examine their structure, chemical composition and microstructure, respectively. Furthermore, the physical and mechanical properties of the sintered nanocomposites were also measured. Moreover, the in vitro bioactivity of the prepared nanocomposites was examined with XRD and SEM. Additionally, the antibacterial behavior of these samples was tested against E. coli and S. aureus by the disc-diffusion method. The results obtained pointed out that the sample with the highest content of BG possessed the best bioactivity, antibacterial effect, physical and mechanical properties.

Tough and self-healing hydrogels based on transient crosslinking by nanoparticles

“…The addition of nanoparticles into the polymer matrix could significantly enhance the mechanical properties. 1–11 Long et al proposed that polymer chains can form binding layers around nanoparticles, which are like carbon-reinforced rubber. 12,13 An alternative explanation proposed by Goritz and Sternstein was that polymer chains can form a “bridge” between nanoparticles, allowing the formation of a percolation network in the system.…”

A Study to Evaluate the Bioactivity Behavior and Electrical Properties of Hydroxyapatite/Ag2O-Borosilicate Glass Nanocomposites for Biomedical Applications

“…However, at least to the knowledge of the authors, the study of HA/borosilicate bioglass nanocomposites still needs great attention; especially with measuring their electrical properties. In our attempt to contribute to highlighting these important nanocomposites, the effect of adding low contents of borosilicate, up to 20%, to HA was studied, and it was found that this addition was effective in improving its mechanical and bioactivity [21]. In continuation of these efforts, the present work is concerned with adding glass, with relatively higher contents up to 32%, to HA and raising the sintering temperature to 750 C and studying the effect of these factors on the in vitro bioactivity, mechanical and electrical properties of these nanocomposites.…”

Evaluation of the Dynamic Behavior, Elastic Properties, and in Vitro Bioactivity of Some Borophosphosilicate Glasses for Orthopedic Applications

“…Over the past few decades, many articles have studied the bioactivity of borophosphate [27][28][29], borosilicate [30][31][32], and phosphosilicate glasses and glass-ceramics [33][34][35]. However, the bioactivity of borophosphosilicate glasses with a detailed prediction of the behavior of these glasses when implanted in the human body under body weight, investigate and explore the effect of increased loads and their relationship to the de ection that occurs in the structure of the samples and whether the bioactive glass samples will undergo yield or fracture has not been previously studied.…”