Synthesis, Spectroscopic and Structural Characterization of New RuII and RuIII Complexes Containing Triazole- and Thiadiazole-Type Ligands

Ruthenium-Catalyzed Isomerization of Allylic Alcohols: Oxidation State Determines Resistance Against Diene Inhibition

“…CHCl 3 is known to contain traces of HCl and recently the syntheses of several complexes with the general formula [RuCl 3 (dmso)L], where L is triazole, thiadiazole or diamine, by oxidation with HCl were reported. [17,18] Indeed, it proved feasible to prepare 1 by oxidation of cis-[RuCl 2 (dmso) 4 ] with HCl in the presence of phen [see (a) and (b) in Scheme 4]. The formation of an Ru III species from an Ru II precursor can be envisioned to involve simultaneous reduction of the dmso ligand to dimethyl sulfide as proposed by Cingi et al [see Equation (1)].…”

“…The formation of an Ru III species from an Ru II precursor can be envisioned to involve simultaneous reduction of the dmso ligand to dimethyl sulfide as proposed by Cingi et al [see Equation (1)]. [17] A general path to the Ru II species that does not invoke ligand participation is discussed below. The roomtemperature route [see (a) in Scheme 4] results directly in analytically pure 1, but the overall yield with the high-temperature route [see (b) in Scheme 4] is higher.…”

“…Both rutheniumϪnitrogen distances are in the range found for other ruthenium complexes with aromatic nitrogen donor ligands. [13,17] The Ru(1)ϪS (21) bond is longer than in analogous Ru II complexes, [17] which reflects the smaller degree of π-back donation in this Ru III complex. The S(21)ϪO(22) bond [1.478(2) Å ] is slightly shorter than in free dmso [1.492(1) Å ] [19] indicating greater SϪO double-bond character in the S-bonded dmso.…”

Differences in structure, physiological stability, electrochemistry, cytotoxicity, DNA and protein binding properties between two Ru(III) complexes

“…As proposed by Cingi et al, Ru(II) is oxidized to Ru(III) by DMSO when HCl is present, during which DMSO is reduced to (CH 3 ) 2 S [34]. Complex 1 is then formed by substitution of DMSO in 2 by CH 3 CN.…”

Synthesis, structural characteristics, DNA binding properties and cytotoxicity studies of a series of Ru(III) complexes

“…3 and 4 are obtained by using cis-[RuCl 2 -(dmso) 4 ] as the starting material. As proposed by Cingi et al, the Ru(II) precursor is oxidized to Ru(III) by dmso when HCl is present[53].The structures of 3 and 4 are confirmed by X-ray diffraction. The crystal structures are shown in Figs.…”