Synthesis of ZnO nanoparticles using Melia dubia leaf extract and its characterisation

Abstract

The present work deals with the synthesis of zinc oxide (ZnO) nanoparticles (Nps) using the biocompounds extracted from leaves (MD L.) and zinc acetate as precursors. The choice of the precursors was based on the intention to use the synthesised ZnO Nps for the healthcare applications. In this line, the antimicrobial property of ethanolic extract of MD L., uncalcined ZnO Nps and calcined ZnO Nps has been assessed and compared. The prepared particles have been characterised by comparing their Fourier transform infrared spectrum, X-ray diffraction (XRD) diffractogram and TEM images. The presence of ZnO has been confirmed using IR spectrum. The crystal structure and crystallite size have been found out using XRD diffractogram, and the obtained crystallite size was confirmed using TEM images. Finally, an attempt has been made to correlate the structure with the antimicrobial property of the material.

Comparative evaluation of the antibacterial and cytotoxic activity of green synthesized and commercially available ZnO nanoparticles

“…The greater zeta potential of green synthesized ZnONPs compared to that of the commercial one, suggests that the green synthesized nanoparticles are more stable in aqueous medium, which in turn is beneficial for its biological applications. Essential stabilization and capping of green synthesized ZnONPs were possibly due to the presence of numerous phytochemicals in the leaf extract, as revealed by the results of FTIR analysis, which are in accordance with literature (11,14). This study, therefore, indicates that eco-friendly ZnONPs can be synthesized by a much easier procedure in comparison to the conventional, hazardous and costly chemical synthesis methods.…”

“…10 ml of 1 M NaOH was added drop wise into this solution. A characteristic yellowish white precipitate was instantly visible right after the addition of NaOH solution (11).…”

Green cardamom mediated phytosynthesis of ZnONPs and validation of its antibacterial and anticancerous potential

“…Powder x-ray diffraction (XRD) performed using x-ray powder Diffractometer model D8, Bruker AXS, Wisconsin, USA was implemented to investigate the crystal morphology of synthesized ZnONPs [43]. As a target, Cu-Kα was used with a wavelength of 1.5418 Å (angstrom) within the 2θ (theta) range of 20-80°and 1 s (second)/step speed of scan were maintained while operating at 35 kV (kilovolt).…”

“…The size (average) of nanoparticle was calculated with the help of the highest peak by Debye-Scherer equation[56]. D=0.9λ/β cosθ (λ, the wavelength is 1.5418 Å; θ, Bragg's diffraction angle and β, the full width at half maximum)[43].…”