Synthesis of some novel azido/tetrazolothienopyrimidines and their reduction to 2,4‐diaminothieno[2,3‐d]pyrimidines

Abstract

A variety of novel 2,4‐diaminothieno[2,3‐d]pyrimidines has been prepared through the reduction of the corresponding azido/tetrazolothienopyrimidines under acidic conditions.

Synthesis of Some Novel Pyrimidine Derivatives and Investigation of their Electrochemical Behavior

“…Many substituted pyrimidine rings play an important role as analgesic, antipyretic, antihypertensive and anti-inflammatory drugs also as pesticides, herbicides, plant growth regulators and organic calcium channel modulators. [1][2][3][4][5][6][7] Various synthesis methods have been reported in the literature for pyrimidine derivatives. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Most of them are based on the simple Biginelli three component cyclocondensation reaction.…”

Three-component process for the synthesis of 4-amino-5- pyrimidinecarbonitriles under thermal aqueous conditions or microwave irradiation

“…12 Pyrimidines occur in some pesticides, 13 herbicides, and plant growth regulators. 14 Consequently, synthetic methodologies for synthesis of novel pyrimidines or pyrimidine-fused compounds are of particular interests in the medicinal and agrochemical areas. 15,16 Although some pyrimidine synthesetic routes have been known for a long time, the development of alternative and more efficient strategies is of considerable relevance.…”

N‐[4‐(dicyanomethylazo)phenyl]‐2‐saccharin‐2‐ylacetamide in the synthesis of pyridazine and pyrimidine derivatives

“…In continuing search for heterocycles of biological activity [3,4], we thought it worthwile to synthesize pyridazine [5][6][7] and pyrimidine [8][9][10] derivatives of the saccharinyl moiety with the objective of obtaining new biologically active compounds.…”