Synthesis of N-(Silylmethyl)amides of Carboxylic Acids and Related Compounds

I2/TBHP mediated domino synthesis of 2-(2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-N-aryl/alkyl benzamides and evaluation of their anticancer and docking studies

“…15 Carboxamide scaffolds are of immense interest in medicinal chemistry. 16,17 The pharmaceutically important ergot alkaloids such as dehydro ergotamine and ergotamine contain amide linkage. There are many drugs like atorvastatin, valsartan, paracetamol and penicillin available in the market, which contains amide linkage in the nucleus and possesses varied therapeutic activities like antimycobaterial, antimicrobial, antifungal, cytotoxic, antiepileptic and analgesic properties.…”