Synthesis of five-membered heterocycles by [3+2] cycloaddition reactions of sulfur-containing 3,3,3-trifluoropropene derivatives

Abstract

The present minireview provides a survey of literature reports on the application of 3,3,3-trifluoropropene derivatives bearing sulfurcontaining functional groups at positions 1 or 2 in the synthesis of functionalized five-membered heterocycles -pyrroles, pyrrolines, pyrrolidines, tetrahydrothiophenes, pyrazoles, pyrazolines, pyrazolidines, isoxazoles, isoxazolines, isoxazolidines, and triazoles via [3+2] cycloaddition reactions with 1,3-dipolarophiles.

Bioinformatic Study of Ziziphus Jujuba (Rhamnaceae) in Preventing the Growth of Breast Cancer

“…This preventive approach, if widely implemented by international agencies, governments, industry, health professionals, consumers, and consumer advocacy groups, could reduce the global incidence of cancer by 10-20% within 10-25 years [ 12,13] One of the plants that can prevent the growth of breast cancer is Ziziphus jujube (Rhamnaceae) bidara plant [ 14,15,16 ] . The bidara plant has many useful ingredients including protein, calcium, iron, magnesium, vitamins, active compounds such as flavonoids, carotenoids, alkaloids, phenols, quercetin, methyl esters, terpenoids, saponins, and so on [17,18,19,20].…”