“…The development of synthetic methods for highly substituted thiophenols with varying degrees of steric hindrance has been an active field of research (Lloyd-Jones et al, 2008), due in part to the potential of sterically encumbered thiophenols to emulate the active site of sulfur-rich metalloenzymes (Fleischer, 2005). In this context, we developed a series of 2,4-disubstituted thiophenols (Flores-Figueroa et al, 2005, Mondragón et al,2010, among which 2,4-dimethylthiophenol represents a commercially available ligand. In order to assess the steric properties of this thiophenol, we soughtout to prepare a metal-thiolate derivative amenable to structural characterization.…”