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citations
Cited by 85 publications
(37 citation statements)
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References 39 publications
(25 reference statements)
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“…The mushroom tyrosinase (EC 1.14.18.1) (Sigma Chemical Co.) was used for in vitro bioevaluation as described previously with some modifications [4041]. Briefly, 140μL of phosphate buffer (20mM, pH 6.8), 20μL of mushroom tyrosinase (30U/mL) and 20μL of the inhibitor solution were placed in the wells of a 96-well micro plate.…”
Section: Methodsmentioning
confidence: 99%
“…The mushroom tyrosinase (EC 1.14.18.1) (Sigma Chemical Co.) was used for in vitro bioevaluation as described previously with some modifications [4041]. Briefly, 140μL of phosphate buffer (20mM, pH 6.8), 20μL of mushroom tyrosinase (30U/mL) and 20μL of the inhibitor solution were placed in the wells of a 96-well micro plate.…”
Section: Methodsmentioning
confidence: 99%
“…Free radical scavenging activity of amide derivatives was determined based on previously reported methods with few modifications 28,29. The assay solution consisted of 100 µL of DPPH (150 µM) and 20 µL of increasing concentration of test compounds, and the volume was adjusted to 200 µL in each well with DMSO.…”
Section: Methodsmentioning
confidence: 99%
“…Tyrosinase is also responsible for the production of neuromelanin. Excessive production of dopaquinone by oxidation of dopamine results in neuronal damage and cell death [37]. For this reason, this enzyme contributed to the neurodegeneration associated with Parkinson's disease and other neurodegenerative disease processes [38].…”
Section: Introductionmentioning
confidence: 99%
“…Also, cancers are characterized by abnormalities in tyrosinase activity [39]. Tyrosinase is also associated with the host defense, wound healing, melting, and sclerotization of insects [40]. Tyrosinase inhibitors were widely used in food, agriculture, and cosmetic industries and in the control of molting process of insects.…”
Section: Introductionmentioning
confidence: 99%