Synthesis, crystal structures, two-photon absorption and biological imaging application of two novel bent-shaped pyrimidine derivatives

Tang, Chao; Zhang, Qiong; Li, Dandan; Zhang, Jun; Shi, Pengfei; Li, Shengli; Wu, Jieying; Tian, Yupeng

doi:10.1016/j.dyepig.2013.04.016

Cited by 22 publications

(13 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This means T-1 has a better planarity of π center. The structural features indicate that the coplanarity of the two compounds is appropriate, which is a necessary condition for preferable nonlinear optical properties [ 27 ].…”

Section: Resultsmentioning

confidence: 99%

A Series of Imidazole Derivatives: Synthesis, Two-Photon Absorption, and Application for Bioimaging

Zhu

Xiao

Zhao

et al. 2015

BioMed Research International

Self Cite

View full text Add to dashboard Cite

A new series of D-π-A type imidazole derivatives have been synthesized and characterized. Two corresponding imidazolium salts (iodine and hexafluorophosphate) were prepared from the imidazole compound. Their electron-withdrawing ability can be largely tunable by salt formation reaction or ion exchange. UV-vis absorption and single-photon fluorescence spectra have been systematically investigated in different solvents. The two-photon cross sections (δ 2PA) of the imidazole derivatives are measured by two-photon excited fluorescence (2PEF) method. Compared with those of T-1 (107 GM) and T-3 (96 GM), T-2 (imidazolium iodine salt) has a large two-photon absorption (2PA) cross section value of 276 GM. Furthermore, the cytotoxicity and applications in bioimaging for the imidazole derivatives were carried out. The results showed that T-1 can be used as a lysosomal tracker with high stability and water solubility within pHs of 4–6, while T-2 and T-3 can be used as probes for cell cytoplasm.

show abstract

Section: Resultsmentioning

confidence: 99%

A Series of Imidazole Derivatives: Synthesis, Two-Photon Absorption, and Application for Bioimaging

Zhu

Xiao

Zhao

et al. 2015

BioMed Research International

Self Cite

View full text Add to dashboard Cite

show abstract

“…Numerous 4,6‐diarylvinylpyrimidines have been obtained by condensation of aldehydes with 4,6‐dimethylpyrimidines either in basic, or acidic media ,. Only a few examples of unsymmetrical 4,6‐dimethylpyrimidines prepared by successive condensation reactions have been described ,.…”

Section: Arylvinylpyrimidinesmentioning

confidence: 99%

Photoluminescence Properties of Aryl‐, Arylvinyl‐, and Arylethynylpyrimidine Derivatives

2018

View full text Add to dashboard Cite

The extraordinary richness of push-pull molecules that incorporate pyrimidine rings as electron-withdrawing moieties in their structure is illustrated in this review. Interest in these pextended systems has increased dramatically over the last two decades due to their fluorescence properties and potential applications in sensing and as luminescent materials. As many as 422 different molecules are presented in an effort to establish structure-property relationships, which are often difficult to elucidate.[a] Dr.

show abstract

“… Tang et al. reported two pyrimidine‐based chromophores with bent‐shaped D‐π‐A‐π‐D motif, namely Z1 and Z2 which showed both strong two‐photon excited fluorescence (2PEF) and large 2PA cross‐sections in the near‐IR region for biological fluorescent probes . Ftouni et al.…”

Section: Two‐photon Fluorescent Probesmentioning

confidence: 99%

Multiphoton Excited Fluorescent Materials for Frequency Upconversion Emission and Fluorescent Probes

Guo

Wong

2014

Advanced Materials

View full text Add to dashboard Cite

Recent progress in developing various strategies for exploiting efficient MPA fluorophores for two emerging technological MPA applications including frequency upconversion photoluminescence and lasing as well as 2PA fluorescence bioimaging and biosensing are presented. An intriguing application of MPA frequency-upconverted lasing offers opportunity for the fabrication of high-energy coherent light sources in the blue region which could create new advantages and breakthroughs in various laser-based applications. In addition, multiphoton excitation has led to considerable progress in the development of advanced diagnostic and therapeutic treatments; further advancement is anticipated with the emergence of various versatile 2PA fluorescence probes. It is widely appreciated that the two-photon excitation offers significant advantages for the biological fluorescence imaging and sensing which includes higher spatial resolution, less photobleaching and photodamage as well as deeper tissue penetration as compared to the one-photon excited microscopy. To be practically useful, the 2PA fluorescent probes for biological applications are required to have a site-specificity, a high fluorescence quantum yield, proper two-photon excitation and subsequent emission wavelengths, good photodecomposition stability, water solubility, and biocompatibility besides large 2PA action cross-sections.

show abstract

Synthesis, crystal structures, two-photon absorption and biological imaging application of two novel bent-shaped pyrimidine derivatives

Cited by 22 publications

References 55 publications

A Series of Imidazole Derivatives: Synthesis, Two-Photon Absorption, and Application for Bioimaging

A Series of Imidazole Derivatives: Synthesis, Two-Photon Absorption, and Application for Bioimaging

Photoluminescence Properties of Aryl‐, Arylvinyl‐, and Arylethynylpyrimidine Derivatives

Multiphoton Excited Fluorescent Materials for Frequency Upconversion Emission and Fluorescent Probes

Contact Info

Product

Resources

About