Eur. J. Chem. volume 6, issue 4, P417-421 2015 DOI: 10.5155/eurjchem.6.4.417-421.1310 View Full Text
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Muhammad Islam, Zahid Shafiq, Mazhar Hussain, Hafiz Badaruddin Ahmad, Muhammad Ajaz Hussain

Abstract: Some novel imine derivatives (1-14) of a broad spectrum antibiotic amoxicillin were prepared by condensation with different carbonyl compounds. The amoxicillin imine derivatives were characterized using elemental analysis and spectroscopic techniques such as FT-IR and 1 H NMR. The prepared imine derivatives were evaluated for antimicrobial activities against some pathogens using disc diffusion method. The results of present studies demonstrate enhanced antimicrobial activity of the novel imine derivatives of …

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