Synthesis, characterization and antimicrobial activity of important heterocyclic acrylic copolymers

Abstract

Abstract. The acrylate monomer, 7-acryloyloxy-4-methyl coumarin (AMC) has been synthesized by reacting 7-hydroxy-4-methyl coumarin, with acryloyl chloride in the presence of NaOH at 0-5°C. Copolymers of 7-acryloyloxy-4-methyl coumarin (AMC) with vinyl acetate (VAc) were synthesized in DMF (dimethyl formamide) solution at 70±1°C using 2,2′-azobisisobutyronitrile (AIBN) as an initiator with different monomer-to-monomer ratios in the feed. The copolymers were characterized by Fourier transform infra red (FTIR) spectroscopy. The copolymer composition was evaluated by 1 H-NMR (proton nuclear magnetic resonance) and was further used to determine reactivity ratios. The monomer reactivity ratios for AMC (M1)-VAc (M2) pair were determined by the application of conventional linearization methods such as Fineman-Ross (r1 = 0.6924; r2 = 0.6431), Kelen-Tüdõs (r1 = 0.6776; r2 = 0.6374) and extended Kelen-Tüdõs (r1 = 0.6657; r2 = 0.6256). Thermo gravimetric analysis showed that thermal decomposition of the copolymers occurred in single stage in the temperature range of 263-458°C. The molecular weights of the polymers were determined using gel permeation chromatography.The homo and copolymers were tested for their antimicrobial properties against selected microorganisms.

A Novel and Efficient Synthesis of [1,2,3]-Triazolyl Substituted Benzo[<i>c</i>]Coumarins and Evaluation of their Antimicrobial Activity

“…All the compounds were routinely checked for completion of the reaction on silica gel 60 F254 TLC plates and their spots were visualized by exposure to a UV lamp, iodine vapour or KMnO4 reagents. Compounds 3-coumarinoyl methyl pyridinium bromide salts (1a-c) [38]- [40] and 1-(5-methyl-1-aryl-1H-1,2,3-triazol-4-yl)ethanones (2a-d) [41] were prepared according to literature procedure.…”

Synthesis, Characterization and Biological Activity of Thiourea Containing Polymers

“…Solubility studies [12] Solubility of the synthesised monomer and the produced polymers is tested in various polar and non-polar solvents. About 5-10 mg of the sample is added to about 2 ml of the solvent in a test tube and kept overnight with the tube tightly closed.…”

“…M. G. Patel et al synthesized 2,4-Dichlorophenyl-acrylate monomer from 2,4-Dichlorophenol and acryloyl chloride. Homo-and copolymers with 2-Hydroxyethylmethacrylate were synthesized by free radical solution polymerization [5]. H. J. Patel et al synthesized the acrylate monomer, 7-acryloyloxy-4-methyl coumarin and its homo-and copolymers with vinyl acetate [6].…”

“…Homo-and copolymers with 2-Hydroxyethylmethacrylate were synthesized by free radical solution polymerization [5]. H. J. Patel et al synthesized the acrylate monomer, 7-acryloyloxy-4-methyl coumarin and its homo-and copolymers with vinyl acetate [6]. Considerable efforts have been made to study the thermal characteristics of polymers using thermogravimetric analysis (TGA), because it analyzes the degradation response and determines the upper temperature limit of use and durability [5,7,8].…”

Properties of solvent-borne acrylic pressure-sensitive adhesives synthesized by a simple approach

“…However, for the high value applications such as the application for LCD protective film, the strict requirements for PSAs must be met which include the appropriate peel strength, defect-free, and anti-curvature so that the optical films can cope with the up-to-date technical trends for high quality products. It is well known that various materials can be used as adhesives [3][4][5], among which acrylic polymers are the most popular ones for PSA applications because of the inherent unique properties [6]. Acrylic PSAs are transparent, colorless, anti-aging against solar radiation and resistant to oxidation [7].…”