Synthesis and properties of new thermosensitive polymer systems

Bohrisch, Jörg; Hahn, Mathias; Maedler, Andrea; Stoll, Michael

doi:10.1002/app.23683

Cited by 4 publications

(5 citation statements)

References 41 publications

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“…However, the catalyst ensures a rapid elimination of the OH‐group from the COOH group and the following formation of H 2 O by H addition to the OH‐group from the added PEG. There are several papers that confirm the possibility of obtaining a PEG–M–PEG complex in this way 19–21…”

Section: Methodssupporting

confidence: 70%

“…A series of peaks between 13 and 16 min indicates different compounds of S–PEG150–SS (horizontal hachure) with different molar masses. Multiple condensation leads to polyelectrolytes that have inherent mechanical properties 19. The area under the curve (vertical and horizontal hachures) was calculated and normalized to one to permit a comparison of S–PEG150–SS molecule and condensation compounds.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Conductive Polymer for Elevated Temperature Applications Based on Sodium Sulfosuccinate Coupled Poly(ethylene glycol)s

Zimmerer¹,

Nagel²,

Steiner³

et al. 2011

Macro Chemistry & Physics

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Sodium sulfosuccinate coupled poly(ethylene glycol) (PEG) (S–PEG–SS) conductive polymers for hot melt adhesives are synthesized from PEG, maleic anhydride, and sodium hydrogen sulphite using a one‐pot three‐step reaction. Infrared spectroscopy and 1H NMR spectroscopy are used to characterize the molecular structure and to determine the yield of esterification. S–PEG150–SS has the highest yield of esterification, whereas S–PEG2000–SS provides the lowest yield of esterification. Gel permeation chromatography and shear viscosity measurements are applied to characterize multiple condensation products and to describe the viscoelastic properties. The results reveal that the viscoelastic properties and the conductivity depend on molar mass of esterified PEG, on the degree of condensation, and on the concentration of ions.

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Section: Methodssupporting

confidence: 70%

Section: Resultsmentioning

confidence: 99%

Conductive Polymer for Elevated Temperature Applications Based on Sodium Sulfosuccinate Coupled Poly(ethylene glycol)s

Zimmerer¹,

Nagel²,

Steiner³

et al. 2011

Macro Chemistry & Physics

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“…In the past, Bohrisch et al . stabilized hydrogels with a crosslinked polystyrene casing . We adopted this idea by embedding ssDNA into a hydrogel sphere and coated it with a shell of crosslinked polystyrene.…”

Section: Introductionmentioning

confidence: 99%

“…In the past, Bohrisch et al stabilized hydrogels with a crosslinked polystyrene casing. 8 We adopted this idea by embedding ssDNA into a hydrogel sphere and coated it with a shell of crosslinked polystyrene. By use of these polystyrene-hydrogel microcapsules we aimed to enhance ssDNA stability against acidic environments for the use as a marking system.…”

Section: Introductionmentioning

confidence: 99%

Enhancing ssDNA stability at acidic pH by encapsulation for the usage as DNA marking system

Stenzel

Bohrisch

Meyer

2014

J of Applied Polymer Sci

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The usage of synthetic single-strand DNA (ssDNA) as an invisible barcode is critical for products, which are exposed to DNA damaging influences during their production or handling (ultraviolet light, acidic conditions, and high temperatures). Encapsulation may protect ssDNA against hydrolytic attack under acidic conditions. This assumption was proved by embedding ssDNA into a spherical hydrogel matrix of polyacrylamide and coating it with a crosslinked polystyrene shell. After acidic treatment of these capsules, the ssDNA stability was measured by detecting the amplification ratio over time with quantitative real-time polymerase chain reaction and calculating the apparent rate constant and apparent half-life. The results of the quantitative detection of ssDNA damage demonstrated that enhancing ssDNA stability by encapsulation with crosslinked polystyrene is possible. Such a potential application may be used in all fields of traceability and of combating counterfeiting, where protection of DNA against environmental influences is needed, for example, as safe marking system for paper, biomaterials, textiles, or leather

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“…Thermo‐responsive polymers have drawn increasing attention in academic and industrial research. Investigation has been focused mostly in the biological and medical fields, such as drug delivery 1–7, tissue engineering 8, biotechnological devices 9, 10, immobilization of enzymes 11 and DNA separation or sequencing 12–19. These thermally sensitive polymers exhibit a “switchable viscosity” that is driven by volume‐phase transition responding to small variations in temperature.…”

Section: Introductionmentioning

confidence: 99%

Reduced matrix viscosity in DNA sequencing by CE and microchip electrophoresis using a novel thermo‐responsive copolymer

Wan

Zhang

et al. 2009

Electrophoresis

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High viscosity is an inherent problem of sequencing matrices made of hydrophilic polymers. This problem is amplified in separations using microchips where the channels are even smaller. A novel thermal associating graft copolymer, using linear polyacrylamide (LPA) as the backbone and poly(propylene oxide) (PPO) as the graft side chain was synthesized. The injection problem could be resolved by introducing PPO side chains that can be assembled by using temperature changes but without an obvious detrimental effect on the sieving ability of the LPA. Viscosity measurement showed that these LPA-g-PPO copolymers had a transition temperature of ~ 40 °C, above which a significant increase in viscosity was observed. The sequencing performance depended on the thermal association properties of PPO and related parameters. Without optimization, a read length of 1000 bases with a single base resolution of 0.3 was achieved within an hour on an ABI 310 analyzer, using 1.8 wt% LPA-g-PPO (1.8 MDa, PPO, 0.2%). This novel thermal reversible copolymer solution can be a promising candidate as a viable matrix for DNA sequencing in capillary electrophoresis, and even more so in microchip electrophoresis.

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Synthesis and properties of new thermosensitive polymer systems

Cited by 4 publications

References 41 publications

Conductive Polymer for Elevated Temperature Applications Based on Sodium Sulfosuccinate Coupled Poly(ethylene glycol)s

Conductive Polymer for Elevated Temperature Applications Based on Sodium Sulfosuccinate Coupled Poly(ethylene glycol)s

Enhancing ssDNA stability at acidic pH by encapsulation for the usage as DNA marking system

Reduced matrix viscosity in DNA sequencing by CE and microchip electrophoresis using a novel thermo‐responsive copolymer

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