Synthesis and evaluation of a novel water-soluble high Se-enriched Astragalus polysaccharide nanoparticles

Meng, Yongbin; Zhang, Yuanyuan; Jia, Nan; Qiao, Huiru; Zhu, Minghua; Meng, Qinghuan; Lü, Qi; Zu, Yuangang

doi:10.1016/j.ijbiomac.2018.06.153

Cited by 31 publications

(13 citation statements)

References 37 publications

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“…Results obtained in this study were comparable or even higher in absolute value (meaning higher stability) than those obtained by other authors who synthesized SeNPs under different approaches. Meng et al obtained a Z -potential value of −20.39 mV [61], while Menon et al reported −36 mV [36], Luesakul et al indicated 14.1 mV [62] and finally −23.2 mV was the average Z -potential value obtained by Cui et al [50], for instance. To conclude, the use of microwave-assisted synthesis supported by CBSE resulted in highly stable SeNPs.…”

Section: Resultsmentioning

confidence: 99%

Microwave-Assisted Green Synthesis and Antioxidant Activity of Selenium Nanoparticles Using Theobroma cacao L. Bean Shell Extract

2019

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Selenium nanoparticles (SeNPs) are successfully synthesized through microwave heating by using Theobroma cacao L. bean shell extract as a stabilizing and capping agent. Response surface methodology is used to obtain optimal synthesis conditions. The effect of microwave power, irradiation time and amount of Na2SeO3 are evaluated on crystalline size by X-Ray Diffraction (XRD) and Z-potential by Dynamic Light Scattering (DLS) using a central composite design (CCD). Optimal synthesis conditions are determined as 15.6 min, 788.6 W and 0.14 g of sodium selenite using 50 mL of Theobroma cacao L. bean shell extract. The successful biosynthesis of SeNPs is confirmed by UV-visible and Fourier Transformed Infrared (FTIR) spectroscopic analyses. The XRD pattern and Raman spectra show the presence of trigonal and amorphous synthesized SeNPs. Spherical SeNPs are observed by Transmission Electron Microscopy (TEM) with a particle size of 1–3 nm in diameter, at least one order of magnitude lower than those previously reported. The obtained SeNPs can be stable up to 55 days at 4 °C. Additionally, the SeNPs show an excellent antioxidant performance by the 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and ferric reducing antioxidant power (FRAP) methods, with potential application in different sectors, such as food, medical and pharmaceutical.

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Section: Resultsmentioning

confidence: 99%

Microwave-Assisted Green Synthesis and Antioxidant Activity of Selenium Nanoparticles Using Theobroma cacao L. Bean Shell Extract

2019

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“…[34] However, it is important to note that DLS and TEM often yield different size data due to the difference in the nature of the measurements. [69,70] DLS reports the hydrodynamic diameter of nanoparticles in their hydrated state, while TEM measures the actual diameter of nanoparticles in their dry state. [28] Therefore, the size measured by DLS is generally larger than that measured by TEM.…”

Section: Structural Characterizationmentioning

confidence: 99%

A Review of Selenium (Se) Nanoparticles: From Synthesis to Applications

Huang,

Chen,

Zeng

et al. 2023

Part & Part Syst Charact

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Selenium is an essential trace element that plays a crucial role in various physiological activities, exerting a significant impact on human health. Selenium deficiency can lead to the development of several diseases, while excessive doses can be toxic. In recent years, there is a growing interest in elemental selenium nanoparticles (SeNPs) due to their good biocompatibility, low toxicity, and high antioxidant activity, making them suitable for numerous applications. The quest for enhancing efficacy and reducing toxicity has driven extensive research on SeNPs. This review aims to provide a comprehensive summary of the recent advancements made in the synthesis, characterization, properties, and applications of SeNPs. Moreover, the challenges associated with SeNPs research, as well as the future trends in the field, are thoroughly discussed. This review aims to provide an insight into the current state of research on SeNPs and highlight areas that require further exploration and development.

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“…In vitro bioactivity of Se-APS-NP was investigated with good bioavailability. It not only increased the T lymphocytes’ cell proliferation and showed high immunoprotective activity, but also inhibited the proliferation of the HepG2 cell line and reduced invasion and cell migration [82] .…”

Section: Advantagesmentioning

confidence: 99%

Metal Ions in Cancer Prevention and Treatment with Traditional Chinese Medicine

Wang,

Myrzagali,

Xie

et al. 2023

Acupuncture and Herbal Medicine

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Malignant tumor has become a major threat affecting human health, and is one of the main causes of human death. Recent studies have shown that many traditional Chinese medicines (TCM) have good anti-tumor activity, which may improve the therapeutic effect of routine treatment and quality of life with lower toxicity. However, the efficacy of TCM alone for the treatment of tumors is limited. Metal ions are essential substances for maintaining normal physiological activities. This article summarized the multiple mechanisms in which metal ions are involved in the prevention and treatment of tumors in TCM.

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Synthesis and evaluation of a novel water-soluble high Se-enriched Astragalus polysaccharide nanoparticles

Cited by 31 publications

References 37 publications

Microwave-Assisted Green Synthesis and Antioxidant Activity of Selenium Nanoparticles Using Theobroma cacao L. Bean Shell Extract

Microwave-Assisted Green Synthesis and Antioxidant Activity of Selenium Nanoparticles Using Theobroma cacao L. Bean Shell Extract

A Review of Selenium (Se) Nanoparticles: From Synthesis to Applications

Metal Ions in Cancer Prevention and Treatment with Traditional Chinese Medicine

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