Synthesis and characterization of thermoresponsive diblock copolymer bearing amino acid moieties via click reaction

Liu, Zhilei; Zhou, Jianping; Liang, Hongbo; Sun, Jianping

doi:10.1007/s00289-011-0619-4

Cited by 3 publications

(2 citation statements)

References 22 publications

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“…Amino acids are biologically important compounds and are often used as the building blocks for synthetic biodegradable polymers with tailor‐made properties . These amino‐acid‐based polymers may have applications as functional biomaterials, in intracellular gene delivery, in making enantioselective membranes, and in tissue engineering . Thus, the amino acids and their derivatives have been used rather widely as functional groups to make functional polymeric materials .…”

Section: Introductionmentioning

confidence: 99%

Amino‐Acid‐Based Zwitterionic Polymer and Its Cu(II)‐Induced Aggregation into Nanostructures: A Template for CuS and CuO Nanoparticles

Banerjee

Maji

Paira

et al. 2013

Macromol. Rapid Commun.

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A convenient and water-based approach is described for the synthesis of an l-lysine-based zwitterionic polymer, poly(ε-l-lysinyl acrylamide) (PLAM), without using protecting group chemistry, chromatographic purifications, and organic solvents as the reaction media. PLAM contains both amine and carboxylic acid groups in each repeating unit, which can either be protonated or deprotonated just by altering the pH of the solution to obtain overall positive or negative charge. PLAM is tested for its applicability as a zwitterionic polymeric buffer in water. Cu(II) ion-induced aggregation of PLAM as a function of solution pH is studied. Spherical nanogel aggregates are formed at pH 9.5 due to aggregation of PLAM through its complexation with Cu(II) ion. Spherical aggregates appear to dissociate via breaking of the complexation at a pH < 5.5 resulting in molecular dissolution of PLAM. This aggregation process is pH reversible. The Cu(II)-PLAM aggregates are used as a template for fabrication of CuO and CuS nanoparticles.

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Section: Introductionmentioning

confidence: 99%

Amino‐Acid‐Based Zwitterionic Polymer and Its Cu(II)‐Induced Aggregation into Nanostructures: A Template for CuS and CuO Nanoparticles

Banerjee

Maji

Paira

et al. 2013

Macromol. Rapid Commun.

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“…Incorporation of amino acids into a polymeric backbone is useful because the amino acids are naturally occurring compounds, and therefore synthetic polymers based on these amino acids are anticipated to be nontoxic, biocompatible, and biodegradable. [10][11][12][13] It seems that poly(amide imide)s (PAIs) with chiral structures based on amino acids are highly biodegradable. Also, PAIs are an important class of material having excellent resistance to high temperatures and favorable balance of other physical and chemical properties.…”

Section: Introductionmentioning

confidence: 99%

In vitrostudies on biodegradable chiral nanostructure poly(amide-imide)s containing different natural amino acids in green medium

Mallakpour

Iderli

Rahimmalek

2013

Designed Monomers and Polymers

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α-Amino acids, as one type of the major building blocks of living systems, are the principal components of all naturally occurring peptides and proteins. The aim of this paper was to synthesize and characterize of novel chiral nanostructured poly(amide-imide)s (PAIs) that are biologically active and biodegradable under a natural environment. PAIs were prepared from the polycondensation reaction of optically active diacids monomers containing different natural amino acids with 4,4′-methylene bis(3-chloro-2,6-diethylaniline) in molten tetrabutylammonium bromide as a green solvent. In vitro fungal colonization and weight loss studies showed that the synthetic polymer having alanine amino acid is biologically more active compared to the other components, nontoxic to microbial growth and could be classified as biodegradable compounds. The synthesized PAIs were characterized by different techniques. The field-emission scanning electron microscopy showed that the obtained PAIs were nanostructured polymers.

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Surface functionalization of cellulose membrane via heterogeneous “click” grafting of zwitterionic sulfobetaine

Huang

et al. 2014

Polym. Bull.

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Synthesis and characterization of thermoresponsive diblock copolymer bearing amino acid moieties via click reaction

Cited by 3 publications

References 22 publications

Amino‐Acid‐Based Zwitterionic Polymer and Its Cu(II)‐Induced Aggregation into Nanostructures: A Template for CuS and CuO Nanoparticles

Amino‐Acid‐Based Zwitterionic Polymer and Its Cu(II)‐Induced Aggregation into Nanostructures: A Template for CuS and CuO Nanoparticles

In vitrostudies on biodegradable chiral nanostructure poly(amide-imide)s containing different natural amino acids in green medium

Surface functionalization of cellulose membrane via heterogeneous “click” grafting of zwitterionic sulfobetaine

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