In vitrostudies on biodegradable chiral nanostructure poly(amide-imide)s containing different natural amino acids in green medium

Abstract

α-Amino acids, as one type of the major building blocks of living systems, are the principal components of all naturally occurring peptides and proteins. The aim of this paper was to synthesize and characterize of novel chiral nanostructured poly(amide-imide)s (PAIs) that are biologically active and biodegradable under a natural environment. PAIs were prepared from the polycondensation reaction of optically active diacids monomers containing different natural amino acids with 4,4′-methylene bis(3-chloro-2,6-diethylaniline) in molten tetrabutylammonium bromide as a green solvent. In vitro fungal colonization and weight loss studies showed that the synthetic polymer having alanine amino acid is biologically more active compared to the other components, nontoxic to microbial growth and could be classified as biodegradable compounds. The synthesized PAIs were characterized by different techniques. The field-emission scanning electron microscopy showed that the obtained PAIs were nanostructured polymers.

Morphological and Thermal Properties of Poly(amide-imide)/ZnO Nanocomposites Derived from 4,4′-methylenebis(3-chloro-2,6-diethyl trimellitimidobenzene) and 3,5-diamino-N-(4-hydroxyphenyl)benzamide

“…First, it avoids using moisturesensitive acid chlorides or isocyanates; second, the use of green solvents such as ILs performed the polymerization reaction under green conditions to report a simple, safe, and efficient method for the synthesis of PAIs. One IL (TBAB), among those employed in our recent works, was selected because it proved to be the most valuable [27][28][29][30][31][32] . The yield and inherent viscosity of the resulting polymer was 92% and 0.50 dL=g, respectively.…”

“…ILs have many advantages, such as extremely low toxicity and volatility, excellent thermal and chemical stability, high ionic conductivity as well as ease of recycling [29][30][31][32][33][34] . So, there is a basic duty for the improvement of new methodologies of polymerizations using environmentally benign media that could replace conventional solvents and enhance adequate solubility for polymerization processes [30] .…”

Facile Approach to Prepare Poly(amide–imide)/ZnO Nanocomposites Derived from L-leucine-Based Diacid and 4,4′-Sulfonyldianiline: Using Ultrasound Irradiation and Ionic Liquid

“…Comparing with the polyimide and polyamide, the PAI own the better heat resistant properties and process ability [7][8][9] . PAI enriched with a naturally amino acid is optically active and biodegradable and has manifest properties such as high thermal stability, good mechanical properties and good chemical resistance [10,11] .…”

New optically active poly(amide-imide)s based on N,N′-(pyromellitoyl)-bis-L-amino acid and methylene diphenyl-4,4′-diisocyanate: synthesis and characterization

“…[1][2][3][4][5] Furthermore, chiral, optically active polyimides (OAPIs) are interesting due to their potential applications for chiral separation and optoelectronic materials used under high-temperature conditions. [6][7][8][9][10][11][12][13][14][15][16][17][18] However, the technological applications of most OAPIs are limited by processing difficulties because of their high melting or glass transition temperatures (T g s) and limited solubility in most organic solvents. [19,20] Therefore, modifications of PI's chemical structure are of great importance so as to overcome the above-mentioned shortcomings.…”