encapsulation and/or (2) covalent or non covalent binding of components that allows the nano-particles to recognize or locate the cancer affected area, permit imaging of the tumor and kill the tumor cells [7].The size of nano particles matters in the imaging. There is a need of nano-particles of the particular size range for EPR (Enhanced Permeation and Retention) effect. The nano-particles only of a specific range can diffuse through the endothelium of tumor tissues to experience the EPR effect. Generally the nanoparticles larger than 10 nm are preferred to avoid the first pass elimination in the kidneys but smaller than 150 nm to 200 nm are used to avoid clearing by the liver and spleen [8].One of the major areas of nano-particles research deals with the cardiovascular diseases (CVD), which includes the targeted imaging of atherosclerosis, restenosis and CVD conditions. The targets for the detection of and imaging of atherosclerotic plaque include fibrin, tissue factor, endothelia, macrophages, collagen III and angiogenesis marker [9]. The use of multifunctional nanoparticles complexes, conjugated with cell specific ligand, makes it possible to deliver therapies directly to the plaques.Nanomedicine may provide the solution for one of the foremost challenges faced by the pharmaceutical industry that is the drug delivery across the blood brain barrier (BBB). The BBB is the tightly packed layer of endothelial cells that surrounds the brain and keeps high molecular weight molecules away from entering. Only small number of drugs or small molecules with high lipid solubility or low molecular weight (less than 400-500 Daltons) can penetrate BBB. In as much as the nano-particles having small size and molecular weight, they are able to move across the BBB. The nano-carriers conjugated with ligands that attach to the brain endothelial cell receptors accumulate there and eventually internalized by cells on the vascular side of the brain through the mechanism of receptor mediated endocytosis [10].