Synthesis and Characterization of Fe<sub>3</sub>O<sub>4</sub> Coated on APTES as Carriers for Morin-Anticancer Drug

Abstract

Morin (MR) is an anticancer drug present in fruits and Chinese herbs. Fe 3 O 4 magnetic nanoparticles (MNPs) coated on 3-aminopropyl triethoxysilane (APTES) were synthesized (MNPs-APTES) as carriers for MR. The characterization of drug delivery system was confirmed by Fourier Transform Infrared (FTIR), Transmission Electron Microscope (TEM), X-Ray Diffraction (XRD), dynamic light scattering (DLS), and vibrating sample magnetometer (VSM). The adsorbed APTES on the magnetite surface (MNPs-APTES) was examined by FTIR. The TEM image showed that the average particle size is obtained to be about 26.7 nm for MNPs-APTES. The MR loading and release behavior of MNPs-APTES were studied and the results showed that up to 60% of the adsorbed drug was released within 4 h. In summary, the MNPs-APTES nanocarriers are based on the results, promising for targeted morin drug delivery.

Recyclable Nanomagnetic Fe3O4@APTES catalyst role on the Hydrolysis of Polycarbonate Wastes

“…3. The position (°2Theta) and the ratio of the intensities of all peaks in the XRD pattern of nano-Fe3O4@APTES are consistent with the XRD pattern of nano-Fe3O4, indicating the preservation of the cubic spinel structure and the non-phase change during coating of the nano-Fe3O4 [41,42]. The average nano-Fe3O4@APTES diameter was estimated to be 29.4 nm from the XRD results with Debye-Scherrer's equation in the °2 Theta= 35.52°.…”

Kinetic Studies on the Catalytic Degradation of Rhodamine B by Hydrogen Peroxide: Effect of Surfactant Coated and Non-Coated Iron (III) Oxide Nanoparticles

“…The peak at 3424 cm −1 in Figure 2 A was associated to the O-H stretching vibrations arising from the hydroxyl group due to the presence of water molecules associated with Fe 3 O 4 [ 38 ]. The H-O-H bending of water molecules in Figure 2 A is observed at 1631 cm −1 in Fe 3 O 4 NPs [ 39 ]. The FTIR spectrum of SDS@Fe 3 O 4 NPs is shown in Figure 2 B, which displayed a new absorption peak at 1252 cm −1 due to the stretching vibration of S=O groups of SDS and the presence of peaks at 2929 cm −1 and 2842 cm −1 , which were assigned to the stretching mode for aliphatic C-H groups of SDS [ 40 ].…”

Chelating magnetic nanocomposite for the rapid removal of Pb(ii) ions from aqueous solutions: characterization, kinetic, isotherm and thermodynamic studies

“…The two broad bands at 3446 and 1670 cm À1 can be attributed to the N-H stretching vibration and NH 2 bending vibration of free NH 2 group respectively. 27 Furthermore, hydrogen bonds of terminal NH 2 silanols and C-N band also appeared at around 3270 and 1290 cm À1 . The presence of the propyl group was conrmed by C-H asymmetric stretching vibration and symmetric stretching vibration that appeared at 2930 and 2841 cm À1 .…”