Synthesis and antimicrobial activity of Ni(II), Co(II), Zn(II) and Cd(II) complexes of 4-substituted-3-mercapto-5-phenyl-4H-1,2,4-triazoles

Regioselectivity of the monohalogenation of 4-allyl-3-allylamino-1,2,4-triazole-5-thione

“…The development of methods of obtaining new condensed heterocyclic compounds from 1,2,4-triazolethiones is an urgent problem, since these compounds possess a broad spectrum of physiological activity as analgetic, vasodilating, anti-inflammatory, and bactericidal agents and show tranquilizing action [1][2][3]; they are used as highly effective additives to photomaterial [4], and also are inhibitors of corrosion of nonferrous metals and alloys based on them [5] Methods are known for the synthesis of condensed systems from 1,2,4-triazolethiones by heterocyclization of monoallyl-substituted 1,2,4-triazolethiones by the action of halogens [6][7][8][9][10] and mineral acids [10,11], as a result of which the formation of condensed thiazolotriazoles was noted.…”

Platinum(II) complexes with carbazates and hydrazides: Synthesis, spectral characterization, computational modeling, and biological studies

“…This class of compounds, and their analogues have the ability to readily coordinate to a variety of transition metals. In addition, it is known that one way to improve the biological activity of organic compounds is complexing them to a transition metal [1][2][3][4], therefore, many hydrazides complexes have been synthesized and characterized [5][6][7]. Some of these metallic complexes also exhibit interesting biological properties, including antitumoral, antimycobacterial and antibacterial activities [8][9][10][11][12][13][14].…”

Spectroscopic characterization and molecular modeling of novel palladium(II) complexes with carbazates and hydrazides

“…For example, isonicotinic acid hydrazide (isoniazid) is the first-line drug in prevention and treatment of Mycobacterium tuberculosis H37Rv [3]. In addition, the formation of metallic complexes plays an important role in the improvement of their biological activities [4][5][6]. Indeed, many complexes containing hydrazides exhibit remarkable biological properties [7][8][9][10][11][12][13][14][15][16].…”