2016
DOI: 10.13005/ojc/320632
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Synthesis and Antibacterial Activity of 2-Monolaurin

Abstract: Ethanolysis reaction triglyceride from coconut oil using enzyme from lipozyme TL IM has produced a mixture of 2-mono acyl glycerol. Product 2-mono acyl glycerol with a yield of 35% has been achieved in the ratio by weight of triglyceride from coconut oil to dry ethanol is 1:4, temperature of 35°C, the number of lipozyme TL IM 5% (w/w) of the total weight of the reactants and reaction time 12 hours. The 2-monolaurin compound with a purity of 100% and a yield of 30, 1 % successfully separated from 2-mono acyl gl… Show more

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Cited by 15 publications
(24 citation statements)
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“…The presence of free fatty acids in vegetable oil can interfere with the transesterification reaction to produce FAME . For this reason, neutralizing vegetable oils with a weak base solution aid in eliminating the free fatty acids 8 . Based on this fact, vegetable oil with an acid number less than one 1 is qualified as a raw material for transesterification reactions.…”
Section: Hydrolysis Of Fatty Acid Methyl Estermentioning
confidence: 99%
See 1 more Smart Citation
“…The presence of free fatty acids in vegetable oil can interfere with the transesterification reaction to produce FAME . For this reason, neutralizing vegetable oils with a weak base solution aid in eliminating the free fatty acids 8 . Based on this fact, vegetable oil with an acid number less than one 1 is qualified as a raw material for transesterification reactions.…”
Section: Hydrolysis Of Fatty Acid Methyl Estermentioning
confidence: 99%
“…1 . The lipase enzyme catalyst suitable for the use in the ethanolysis reaction is sn-1,3-regiospecific lipase 8,48,49 . The sn-1,3regiospecific lipase is only initiated lysis reaction of the acyl group in position 1 and 3 of the glycerol backbone.…”
Section: Ethanolysis Of Vegetable Oilmentioning
confidence: 99%
“…The Kabate larva, in a local language of Timor Island called, is a larva that can be found in the wounded stem of the Sesbania gradiflora L. tree as shown in Figures 1. A review has reported that antimicrobial activity, as well as anti-fungal of the vegetable oils or animal fats, were not lead to by their triglyceride compositions but their monoacylglycerol (monoglyceride) of their fatty acids 1 . Some examples of monoacylglycerol from fatty acids that reported for having antimicrobial activity i.e.…”
Section: Introductionmentioning
confidence: 99%
“…Some examples of monoacylglycerol from fatty acids that reported for having antimicrobial activity i.e. monolaurin from coconut oil 2,3,4,5,6,7,8 , monocaprin from coconut oil 9 , monomyristin and monolinolein 10 and also monoolein 11 .…”
Section: Introductionmentioning
confidence: 99%
“…Monolaurin is antimicrobial and antiviral activity. Moreover, it is used as anti obesity treatment 10,11,12 .…”
Section: Introductionmentioning
confidence: 99%