Synthesis and amination of 5- and 8-amino derivatives of 2-phenylnaphtho[2,3-d]-1,3-thiazole-4,9-dione

Shishkina, R. P.; Sergienko, N. V.

doi:10.1007/bf00700175

Cited by 3 publications

(1 citation statement)

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“…Only for the significantly electron-donating substituents R = OMe ( 7 ) and R = NH 2 ( 8 ) were single regioisomers observed. The structures of 15 and 16 were assigned by comparison to known reactions with other amines. − All linker molecules used were commercially available apart from N , N ′-dimethylcystamine 4 , prepared in two steps from commercial materials.…”

Section: Resultsmentioning

confidence: 99%

Series of Quinone-Containing Nanosensors for Biologically Relevant Redox Potential Determination by Surface-Enhanced Raman Spectroscopy

Thomson

Camus

et al. 2015

Anal. Chem.

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Redox potential is of key importance in the control and regulation of cellular function and lifecycle, and previous approaches to measuring the biological redox potential noninvasively in real time are limited to areas of hypoxia or normoxia. In this paper, we extend our previous work on nanoparticle-based intracellular nanosensors to cover a much wider redox potential range of -470 to +130 mV vs NHE, which includes the redox potential range occupied by cells in a state of oxidative stress. The nanosensors are rationally designed to target different areas of this redox potential range and are monitored by surface-enhanced Raman spectroscopy, which will permit noninvasive real-time imaging of cells undergoing oxidative stress.

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Section: Resultsmentioning

confidence: 99%