Synthese und Acylierungen des 1‐Hydroxylamino‐adamantans 43. Mitt. über Hydroxylamin‐Derivate

Abstract

Das aus 1-Amino-adamantan und Dibenzoylperoxid erhaltliche 1 -Benzoyloxy-adamantan lies sich in Azoxy-1,l'-adamantan und 1 -Hydroxylamino-adamanhn hydrolysieren, welches in verschiedene Aoyl-Derivate ubergefiihrt wurde. Synthesis and Acylations of 1-Hydroxylamino-adamantme1-Benzoyloxy-adamanhne obtained from 1-amino-adamntane and dibenzoyl peroxide could be hydrolyzed to azoxy-1,l'-adamantane and 1-hydroxylamino-adamantane. The latter was transferred to various acyl-derivatives.

Product Class 5: Hydroxylamines

“…By this methodology (Zinners procedure), 1-and 2-adamantylhydroxylamines are prepared in reasonable yields. [190,191] Scheme 47 Synthesis of N-Alkylhydroxylamines by Oxidation of Primary Amines [190][191][192][193] 148 83 The branched N-alkylhydroxylamines 149 are also prepared by dibenzoyl peroxide oxidation. [192,193] Using 3-chloroperoxybenzoic acid provides the hydroxylamine 151 from the valine derivative 150 in 68% yield.…”