SYNTAX Score II predicts carotid disease in a multivessel coronary disease population

Costanzo, Luca; Capodanno, Davide; Manichino, Daniela; Sole, Andrea; Ronsivalle, Giuseppe; Pino, Luigi Di; Tamburino, C; Giaimo, Valerio; Tamburino, Corrado

doi:10.1016/j.ijcard.2015.06.005

Cited by 5 publications

(5 citation statements)

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“…Compatible with these studies, SS I was not associated with CAS whereas age was an independent predictor of CAS in our study [14] . A latter study by the same group of researchers confirmed a relationship between SS II and CAS [15] . A recent study by Avci et al [13] demonstrated the association between SS I and CAS, however, this association was not independent.…”

Section: Discussionmentioning

confidence: 77%

“…A recent study found CAS as an independent predictor of high SYNTAX score (>32), however, the study population was heterogeneous and comprised patients with single and multivessel disease [16] . Up to date, only a single study investigated the relationship between SS II and CAS [15] . Baseline characteristics and risk factors of patients in this study were similar to ours.…”

Section: Discussionmentioning

confidence: 99%

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Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis

Öztürk¹,

Şahın²

2019

Braz J Cardiovasc Surg

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ObjectiveTo evaluate the predictive accuracy of SYNTAX score (SS) I and II for detecting significant carotid artery stenosis (CAS) in patients with multivessel coronary artery disease undergoing coronary artery bypass grafting (CABG) surgery.MethodsThe study population consisted of 416 patients. Clinical, demographic, and radiological records were retrospectively reviewed. Characteristics of patients with CAS (n=66) and patients without CAS (n=350) were compared before and after propensity score matching analysis.ResultsPatients with significant CAS were older compared to those without significant CAS [(60 (53-65) vs. 63 (59-67); P=0.01]. However, atherosclerotic risk factors and SS I were similar between groups. SS II CABG and percutaneous coronary intervention (PCI) were significantly higher in patients with CAS [37.4 (30.9-43.5) vs. 33.8 (29.9-38.9); P=0.02]. After propensity score matching analysis (66 vs. 66), age, SS II PCI and CABG were significantly higher in patients with CAS than those without CAS [37.4 (30.9-43.5) vs. 33 (29.3-36.9); P=0.03]. Age, SS II PCI and CABG were associated with CAS in logistic regression analysis [OR=1.086, 95% CI (1.032-1.143), P<0.001; OR=1.054, 95% CI (1.010-1.101), P=0.02; OR=1.078, 95% CI (1.029-1.129), P<0.01].In ROC curve analysis, SS II PCI >33.1 had 68.2% sensitivity and 54.6% specificity [AUC=0.624, P=0.01, 95% CI (0.536-0.707)] whereas SS II CABG >26.1 had 81.8% sensitivity and 54.6% specificity [AUC=0.670, P<0.01, 95% CI (0.583-0.749)] to predict CAS. Pairwise comparison of ROC curves revealed similar statistical accuracy for prediction of CAS (z statistic: 0.683, P=0.49)ConclusionSS II is useful to predict asymptomatic CAS in patients with multivessel coronary artery disease.

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Section: Discussionmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 99%

Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis

Öztürk¹,

Şahın²

2019

Braz J Cardiovasc Surg

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“…This was explained by evaluating purely anatomic parameters with Syntax score and, in contrast, the Syntax II score also includes clinical data of patients. Costanzo et al [20] also recommended using the Syntax II score for the carotid artery and coronary artery relationship in their recent study, but for peripheral artery disease and CAD, we recommend using the classical Syntax score (based on our study results [20][21][22][23][24][25].…”

Section: Discussionmentioning

confidence: 99%

Prediction of coronary artery disease severity in lower extremity artery disease patients: A correlation study of TASC II classification, Syntax and Syntax II scores

et al. 2017

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“…1 , 2 , 3 Since 2013, various reports have described alternative markers, which can be potentially used for the improvement of this scoringsystem. 4 , 5 , 6 …”

Section: Introductionmentioning

confidence: 99%

The association of the Syntax score II with carotid intima media thickness and epicardial fat tissue

Aksu

Gülcü

Bilgi

et al. 2017

Indian Heart Journal

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AimSyntax score II (SSII) is a highly predictive scoring system, which is used to improve individualized assessment of patients with complex coronary artery disease and facilitates clinical decision making. Surrogate markers [carotid intima-media thickness (CIMT), epicardial fat tissue (EFT)] are also used for risk assessment, but their relation with SSII is not well established.MethodWe enrolled 543 consecutive patients, who underwent coronary angiography for stable angina pectoris and acute coronary syndrome, in the study. SSII was calculated for each patient and the patients were divided into two groups as low SSII group and high SSII group according to their median SSII.ResultsThe average age of the patients was 61.4 years and 75% of the patients were male. The multivariate analysis indicated that only EFT (p: 0,035), CIMT (p:0,04) and Hypertension (HT) (p: 0,014) were independently associated with high SSII.DiscussionEFT and CIMT, the surrogate markers which can be simply and non-invasively determined, are of the independent predictors of high SSII. The inclusion of these parameters in the risk classification may provide additional clinical benefit.

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SYNTAX Score II predicts carotid disease in a multivessel coronary disease population

Cited by 5 publications

References 47 publications

Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis

Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis

Prediction of coronary artery disease severity in lower extremity artery disease patients: A correlation study of TASC II classification, Syntax and Syntax II scores

The association of the Syntax score II with carotid intima media thickness and epicardial fat tissue

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