“…These observations are likely to result from the lower total number of viable bacteria on the sample surface following the initial bacterial attachment period and early observation timepoints ( Figure 6), which was further confirmed by the significantly reduced number of CFUs observed for the H2O2-treated coated samples at both 4 h and 12 h timepoints ( Figure 5B). Further, similar effects have been observed against S. epidermidis and S. mutans for H2O2-oxidised and H2O aged titanium, 55 and against five strains related to implant-related infections for TiO2…”
Section: Antibacterial Activitysupporting
confidence: 69%
“…25 All these groups related the antibacterial effect to the presence of O2 - The antibacterial activity of the coated surfaces was still observed 24 h after the treatment with H2O2 ( Figures 5 and 6), and therefore, the stability of the oxidative layer in air was found to be higher than that previously reported for UV-irradiated TiO2 surface either with or without exposure to H2O2. 25,55 When in contact with bacterial suspension, the stabilised radicals may be consumed and partly decompose vital bacterial compounds analogous to the degradation of MB (Figure 4). This is supported by the higher number of dead bacteria observed on the modified TiO2 surfaces 4 h after seeding ( Figure 6).…”
“…These observations are likely to result from the lower total number of viable bacteria on the sample surface following the initial bacterial attachment period and early observation timepoints ( Figure 6), which was further confirmed by the significantly reduced number of CFUs observed for the H2O2-treated coated samples at both 4 h and 12 h timepoints ( Figure 5B). Further, similar effects have been observed against S. epidermidis and S. mutans for H2O2-oxidised and H2O aged titanium, 55 and against five strains related to implant-related infections for TiO2…”
Section: Antibacterial Activitysupporting
confidence: 69%
“…25 All these groups related the antibacterial effect to the presence of O2 - The antibacterial activity of the coated surfaces was still observed 24 h after the treatment with H2O2 ( Figures 5 and 6), and therefore, the stability of the oxidative layer in air was found to be higher than that previously reported for UV-irradiated TiO2 surface either with or without exposure to H2O2. 25,55 When in contact with bacterial suspension, the stabilised radicals may be consumed and partly decompose vital bacterial compounds analogous to the degradation of MB (Figure 4). This is supported by the higher number of dead bacteria observed on the modified TiO2 surfaces 4 h after seeding ( Figure 6).…”
“…Viabilities of S. epidermidis and S. mutans were reduced by 99.7% and 98.9% respectively after exposure to 0.1 wt% H 2 O 2 and UV light on TiO 2 surfaces for 20 min, while he corresponding viability reduction was 86% for S. epidermidis and 65% for S. mutans without H 2 O 2 . This study indicated H 2 O 2 can improve the efficiency of photocatalytic TiO 2 surfaces [197].…”
a b s t r a c tBacterial adhesion on dental implants may cause peri-implant disease including peri-implant mucositis and peri-implantitis. Peri-implantitis may lead to bone resorption and eventually loss of the implant. Therefore, the factors which influence bacterial adhesion are critical and revealed by many studies. The purpose of this review is to summarize the current knowledge of factors influencing the bacteria adhesion, including local factors of implant surface topography, abutment, cement and oral environment factors of saliva and protein. In addition, the corresponding strategies of surface modifications, coatings and challenges for implant materials as prevention and treatment approaches for bacteria adhesion on implant will also be discussed. We expect to give an overall picture of the bacteria adhesion on implant, and provide future perspectives, such as laser therapy, photocatalysis, plasma and bioelectric effect to inspire researchers to explore on this issue.
“…207 Further, the formation of a biofilm is characteristic of the infection of dental and orthopaedic implants, and S. epidermidis has been extensively used to study this behaviour in vitro. 114,115,203,208 It readily forms biofilms on various substrates in a monoculture and is less virulent compared to S. aureus. 58 In addition, S. epidermidis grows under aerobic and anaerobic conditions with high tolerance against exogenous oxidative stress.…”
Section: Antibacterial Activity In Vitromentioning
I am indebted to Håvard J. Haugen, Janne Elin Reseland and Ståle Petter Lyngstadaas. I would like to thank you for the inspirational discussions, progress meetings and the encouragement to present my research outside the department. But most importantly, you backed me up when I needed it the most. You have my respect. I never thought that microbiology is fun. That was before I met Jessica Lönn-Stensrud. Thank you for showing me bakterienes forunderlige verden and for being an excellent supervisor. Thanks, Hanna Tiainen, for absolutely everything. You have been a mentor for me and I enjoyed every bit of this three-year-long roller coaster ride. Our intense discussions have been a highlight of my PhD and I would like to thank you for passing on your passion for research. Along the way, I had the privilege to work with several outstanding researchers in their field.
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