Sweet's syndrome associated with Salmonella enteritidis infection

Trendell-Smith²,

et al. 2013

Dermatology

Immunodeficiency due to anti-interferon-gamma autoantibody (anti-IFN-γ autoAb) is an emerging adult-onset immunodeficiency syndrome predominantly found in Southeast Asians. It is associated with severe or disseminated infections caused by non-tuberculous mycobacteria (NTM) and other opportunistic pathogens. We describe 3 patients with anti-IFN-γ autoAb who developed reactive and infective dermatoses, and thoroughly review the existing literature on dermatoses associated with the immunodeficiency syndrome. Case 1 developed Sweet's syndrome associated with Mycobacterium chelonae lymphadenitis and penicilliosis. Case 2 suffered from multiple episodes of lobular panniculitis during recurrent infections by NTM, Penicillium marneffei and Burkholderia pseudomallei. Both cases responded to immunomodulating agents including corticosteroid and non-steroidal anti-inflammatory drugs. Case 3 had direct skin invasion by M. chelonae and responded to prolonged anti-mycobacterial therapy. A novel working algorithm is proposed for the diagnosis and treatment of these patients who may be encountered by the dermatologist and histopathologist in clinical practice.

Section: Discussionmentioning

confidence: 82%

Reactive and Infective Dermatoses Associated with Adult-Onset Immunodeficiency due to Anti-Interferon-Gamma Autoantibody: Sweet's Syndrome and Beyond

Trendell-Smith²,

et al. 2013

Dermatology

“…There are also several conditions for which the association with Sweet's syndrome is possibly bona fide (Table 6). In addition, the validity of the association between Sweet's syndrome and many of the conditions that have been observed in patients with the dermatosis remains to be established (Table 7) (Figure 9); indeed, the detection of that condition in an individual with Sweet's syndrome may merely represent a coincidental occurrence [1,2,5,11-20,30,36-43,69-126,158-161,164,166,186-190,195,214,231,236,259-339,401,404,407,409-411,413,415,417-419,421,424,425,431,433]. …”

Section: Clinical Descriptionmentioning

confidence: 99%

Sweet's syndrome – a comprehensive review of an acute febrile neutrophilic dermatosis

Cohen

2007

Orphanet J Rare Dis

724

1,006

“…Other commonly used drugs reported to cause Sweet's syndrome are antibiotics such as trimethoprimsulfamethoxazole [5], nitrofurantoin [6], antiepileptic drugs such as carbamazepine [7], diazepam [8], diuretics such as furosemide [9], non-steroidal antiinflammatory drugs such as diclofenac [10], and celecoxib [11]. Sweet's syndrome has also been reported following infections of the upper respiratory tract [12,13] and the gastrointestinal tract [14]. Mycobacterium cervical lymphadenitis associated with Sweet's syndrome has been documented in only a few reports [15,16], but sputum-positive pulmonary tuberculosis showing Sweet's syndrome is a very uncommon association.…”

Section: Introductionmentioning

confidence: 99%

Sweet’s syndrome: a very rare association with pulmonary tuberculosis

Karmakar

Sherpa

Ray

et al. 2013

J Infect Dev Ctries

Mycobacterium tuberculosis infection is a common infection in developing countries, including India. It can induce several cutaneous reactions such as erythema nodosum, and erythema induratum; however, association of tuberculosis with Sweet's syndrome (also known as acute febrile neutrophilic dermatosis) is extremely rare. Here we present an interesting case of sputum-positive pulmonary tuberculosis with Sweet's syndrome. A 55-year-old female who was receiving a regimen of four antitubercular drugs (isoniazid, rifampicin, pyrazinamide, ethambutol-HRZE) for six weeks for sputum-positive pulmonary tuberculosis developed new onset high-grade fever for 15 days along with multiple reddish brown plaques and nodules involving the face as well as all four limbs of the body. Histopathology of the skin lesion was suggestive of Sweet's syndrome. The patient responded well to immunosuppressive steroid therapy.