Susceptibility to Kindling and Neuronal Connections of the Anterior Claustrum

Zhang, Xia; Hannesson, Darren K.; Saucier, Deborah M.; Wallace, Amy E.; Howland, John G.; Corcoran, Michael E.

doi:10.1523/jneurosci.21-10-03674.2001

Cited by 70 publications

(90 citation statements)

References 94 publications

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“…These included inputs from the anterior claustrum (very dense), secondary motor cortex, AC, TTd, reticular and paraventricular nuclei of thalamus, SNr, IP, and LDT. Previous reports have similarly shown that SMT is strongly reciprocally connected with the anterior claustrum (Yoshida et al, 1992;Zhang et al, 2001).…”

Section: Comparisons Of Projections To Re With Projections To Adjacenmentioning

confidence: 59%

Afferent projections to nucleus reuniens of the thalamus

Mckenna

Vertes

2004

J of Comparative Neurology

224

225

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The nucleus reuniens (RE) is the largest of the midline nuclei of the thalamus and the major source of thalamic afferents to the hippocampus and parahippocampal structures. Nucleus reuniens has recently been shown to exert powerful excitatory actions on CA1 of the hippocampus. Few reports on any species have examined afferent projections to nucleus reuniens. By using the retrograde anatomical tracer Fluorogold, we examined patterns of afferent projections to RE in the rat. We showed that RE receives a diverse and widely distributed set of afferents projections. The main sources of input to nucleus reuniens were from the orbitomedial, insular, ectorhinal, perirhinal, and retrosplenial cortices; CA1/subiculum of hippocampus; claustrum, tania tecta, lateral septum, substantia innominata, and medial and lateral preoptic nuclei of the basal forebrain; medial nucleus of amygdala; paraventricular and lateral geniculate nuclei of the thalamus; zona incerta; anterior, ventromedial, lateral, posterior, supramammillary, and dorsal premammillary nuclei of the hypothalamus; and ventral tegmental area, periaqueductal gray, medial and posterior pretectal nuclei, superior colliculus, precommissural/commissural nuclei, nucleus of the posterior commissure, parabrachial nucleus, laterodorsal and pedunculopontine tegmental nuclei, nucleus incertus, and dorsal and median raphe nuclei of the brainstem. The present findings of widespread projections to RE, mainly from limbic/limbic-associated structures, suggest that nucleus reuniens represents a critical relay in the transfer of limbic information (emotional/cognitive) from RE to its major targets, namely, to the hippocampus and orbitomedial prefrontal cortex. RE appears to be a major link in the two-way exchange of information between the hippocampus and the medial prefrontal cortex.

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Section: Comparisons Of Projections To Re With Projections To Adjacenmentioning

confidence: 59%

Afferent projections to nucleus reuniens of the thalamus

Mckenna

Vertes

2004

J of Comparative Neurology

224

225

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“…The experiments of Remedios et al (2010), however, show that there is a rapid functional connection between the auditory system and the claustrum. Moreover, Zhang et al (2001), using a similar technique, were able to demonstrate bidirectional connections between the claustrum, on the one hand, and both primary and secondary visual, somatosensory, and auditory cortices on the other.…”

Section: Introductionmentioning

confidence: 89%

Hypotheses Relating to the Function of the Claustrum

2014

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“…As well recognized, the CLA is reciprocally linked to virtually all areas of the cortex, including mPFC (Markowitsch et al 1984;Sloniewski et al 1986;Sherk 1988;Witter et al 1988;Kowianski et al 1998;Majak et al 2000;Zhang et al 2001). Using anterograde tracers, Zhang et al (2001) showed that CLA mainly targets AGm of the mPFC. Consistent with this, retrograde injections in the dorsal mPFC were shown to produce dense cell labeling in CLA (Hur and Zaborszky 2005).…”

Section: Other Inputs To Agmmentioning

confidence: 95%

Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat

2007

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The medial prefrontal cortex (mPFC) has been associated with diverse functions including attentional processes, visceromotor activity, decision making, goal directed behavior, and working memory. Using retrograde tracing techniques, we examined, compared, and contrasted afferent projections to the four divisions of the mPFC in the rat: the medial (frontal) agranular (AGm), anterior cingulate (AC), prelimbic (PL), and infralimbic (IL) cortices. Each division of the mPFC receives a unique set of afferent projections. There is a shift dorsoventrally along the mPFC from predominantly sensorimotor input to the dorsal mPFC (AGm and dorsal AC) to primarily 'limbic' input to the ventral mPFC (PL and IL). The AGm and dorsal AC receive afferent projections from widespread areas of the cortex (and associated thalamic nuclei) representing all sensory modalities. This information is presumably integrated at, and utilized by, the dorsal mPFC in goal directed actions. In contrast with the dorsal mPFC, the ventral mPFC receives significantly less cortical input overall and afferents from limbic as opposed to sensorimotor regions of cortex. The main sources of afferent projections to PL/IL are from the orbitomedial prefrontal, agranular insular, perirhinal and entorhinal cortices, the hippocampus, the claustrum, the medial basal forebrain, the basal nuclei of amygdala, the midline thalamus and monoaminergic nuclei of the brainstem. With a few exceptions, there are few projections from the hypothalamus to the dorsal or ventral mPFC. Accordingly, subcortical limbic information mainly reaches the mPFC via the midline thalamus and basal nuclei of amygdala. As discussed herein, based on patterns of afferent (as well as efferent) projections, PL is positioned to serve a direct role in cognitive functions homologous to dorsolateral PFC of primates, whereas IL appears to represent a visceromotor center homologous to the orbitomedial PFC of primates.

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Susceptibility to Kindling and Neuronal Connections of the Anterior Claustrum

Cited by 70 publications

References 94 publications

Afferent projections to nucleus reuniens of the thalamus

Afferent projections to nucleus reuniens of the thalamus

Hypotheses Relating to the Function of the Claustrum

Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat

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