Survival of CR51 Labeled Erythrocytes in Swine.

Experimental production of siderocytes.

“…The mean half-time disappearance of the 51Cr label was 11.6 days (7 to 15 days) and 17.6 days (14 to 25 days), respectively, in the two groups. In both groups the rate of disappearance of 51Cr-labeled cells was within the normal limits described previously (22,23). These values give a relative but not a true estimate of the rate of cell loss (24) since chromium elutes from the cell, but it is apparent that in spleen-intact animals the disappearance of siderotic granules is considerably more rapid than the disappearance of the cells themselves, in confirmation of the observation of Crosby (1).…”

“…[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] (19)(20)(21)(22)(23)(24)(25)(26) * The values tabulated are the means of the last determinations before discontinuing phlebotomy or phenylhydrazine administration; the figures in parentheses refer to observed range. 3%7o or less within 4 days in both animals.…”

Pig reticulocytes. III. Glucose permeability in naturally occurring reticulocytes and red cells from newborn piglets.

“…Bush et al (1956), using 5ICr, determined the mean half-life to be 17 days in four growing pigs. Talbot and Swenson (1963) by autologous and homologous transfusion techniques found the half-life to be 14 and 28 days, respectively. By taking into account the estimated half-life of fetal cells and the extent of fetal cell dilution and assuming that only glucoseimpermeable cells are produced after birth, it is now possible to construct the rate at which membrane permeability to glucose should decay in the growing piglets.…”

Effects of desferrioxamine and iron on hematologic values, urinary iron, and antiferritin antibody production in the pig

“…The hemoglobin values (Table 16a) in this study compared quite favorably with the values found by Coulter (1965) and to those found by Talbot and Swenson (1963) during the first three weeks of their study.…”