Based on the data flow feature analysis of the MIMO detection algorithms, a more efficient array architecture and a multi-hierarchical routing structure are proposed in the Coarse-Grained Reconfigurable Architecture platform, named Reconfigurable Signal Processor 2.0 (RaSP2.0) in this paper. The proposed design with higher throughput requires less hardware resource and has more efficient routing structure when compared with the first generation of RaSP. Implemented in TSMC 40nm technology, the single core of RaSP2.0 occupies 1.02 mm 2 and is capable of running at 500MHz. The experimental results show that the area of RaSP2.0 reduces 63% compared with RaSP when normalized to 96-order matrix inversion operation. The hardware efficiency of QR decomposition (QRD) operation in the case of 4×4 matrix is improved by 1~3.17 times than the other architectures. In addition, the RaSP2.0 can realize the 96-order matrix inversion operation via only one single mapping, which can provide higher throughput.