Surgical outcomes of secondary and tertiary hyperparathyroidism in King Salman Armed Forces Hospital, Tabuk

Abstract

Objective: To investigate surgical outcomes of tertiary and secondary hyperparathyroidism in King Salman Armed Forces hospital, Tabuk, Saudi Arabia. Methods: A record-based research that was retrospective in nature was carried out between January 1, 2015 and August 1, 2022. The King Salman Armed Forces hospitals' documents were gathered, including all valid surgical records. A predesigned data collection pro forma was used to capture the data, which was then revised, coded and entered into the statistical programme IBM SPSS version 22. Results: 17 patients who had undergone hyper parathyroidectomy surgery and had a clinical diagnosis of hyperparathyroidism were included in the research. Among the patients, 11.8% had CKD and 88.2% also had hypertension. Following surgery, mean (SD) calcium levels substantially decreased from 2.31 (0.36) to 2.10 (0.29) (P=0.029). Additionally, there was a substantial decrease in phosphate mean levels from 2.06 (0.90) to 1.38 (0.63) (P=0.047). Additionally, there was a substantial decrease in creatinine levels from 752.52 (305.91) to 544.41 (301.33) (P=0.024). A substantial decrease in PTH mean levels was also observed, going from 1888.76 (77.38) pre-operative to 494.42 (577.74) post-operative (P=0.013). 35.7% of patients had hypocalcaemia and 11.8% had hematomas as post-operative complications. Conclusion: In individuals with chronic renal disease, complete parathyroidectomy with auto-transplantation is a safe and efficient method of treating tertiary and secondary hyper parathyroid disorders. The study sample did not have any recurrence, and the incidence of complications was quite low.